Search for dissertations about: "Crc"

Showing result 1 - 5 of 145 swedish dissertations containing the word Crc.

  1. 1. Biomarkers for Diagnosis, Therapy and Prognosis in Colorectal Cancer : a study from databases, machine learning predictions to laboratory confirmations

    Author : Xueli Zhang; Hong Zhang; Xiao-Feng Sun; Dirk Repsilber; Bairong Shen; Mauno Vihinen; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; diagnosis; therapy response; prognosis; database; machine learning; CRC;

    Abstract : Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. Early diagnosis and better therapy response have been believed to be associated with better prognosis. CRC biomarkers are considered as precise indicators for the early diagnosis and better therapy response. READ MORE

  2. 2. Lung Metastases - Diagnostic, Prognostic and Molecular Aspects with Focus on Colorectal Cancer

    Author : Halla Vidarsdottir; Förbättrad diagnostik och prognostik vid lungcancer och metastaser till lunga; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lung cancer; lung metastasis; tissue microarray; TTF-1; napsin A; cytokeratin; GATA3; CDX2; PAX8; CRC; pulmonary metastasectomy; RBM3; recurrence; survival; NGS; Trusight tumor 26; Trusight Oncology 500;

    Abstract : In Sweden 4200 patients are diagnosed with lung cancer and 6500 patients with colorectal cancer (CRC) annually. The lungs are a common site for metastases. Immunohistochemistry (IHC) is a helpful aid in diagnostics of a pulmonary tumour. READ MORE

  3. 3. Multiple regulatory inputs for hierarchical control of phenol catabolism by Pseudomonas putida

    Author : W. K. Anjana Madhushani; Victoria Shingler; Livia Leoni; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; P. putida; Phenol catabolism; dmpR; dmp-System; 5’-LR; Carbon Catabolite Repression; Transcriptional Translational regulation; Crc; CrcZ; CrcY; Hfq;

    Abstract : Metabolically versatile bacteria have evolved diverse strategies to adapt to different environmental niches and respond to fluctuating physico-chemical parameters. In order to survive in soil and water habitats, they employ specific and global regulatory circuits to integrate external and internal signals to counteract stress and optimise their energy status. READ MORE

  4. 4. Circulating markers of risk and etiology in colorectal cancer

    Author : Justin Harbs; Sophia Harlid; Bethany van Guelpen; Xijia Liu; Henrik Grönberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; CRC; sex hormones; colon cancer; DNA methylation; proteomics; risk; etiology; Cancer Epidemiology; cancerepidemiologi;

    Abstract : Background: Colorectal cancer is the third most commonly diagnosed cancer in men and women. Worldwide around 2 million individuals are diagnosed each year – a number expected to increase as colorectal cancer risk factors become more prevalent. READ MORE

  5. 5. DNA methylation in the placenta and in cancerwith special reference to folate transporting genes

    Author : Sanja Farkas; Torbjörn Nilsson; Lars Breimer; Warren D. Kruger; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA methylation; CRC; placenta; cervix; leukocytes; T-DMRs; folate; array; expression; Biomedicin; Biomedicine;

    Abstract : DNA methylation is an epigenetic mechanism that regulates the gene transcription. Folate is used in cellular synthesis of methyl groups, nucleic acids and amino acids. In complex diseases like cancer and neural tube defects (NTD), various genetic and epigenetic alterations can be found that disrupt the normal cell function. READ MORE