Search for dissertations about: "Cryo-electron tomography"

Showing result 1 - 5 of 14 swedish dissertations containing the words Cryo-electron tomography.

  2. 1. Cryo-electron tomography of individual protein molecules

    Author : Sara Sandin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cryo-Electron Microscopy; Cryo-Electron Tomography; Protein Conformation; Antibodies; Immunoglobulin G; Glucocorticoid Receptor; Hepatocyte Growth Factor Scatter Factor; Receptor Tyrosine Kinase MET;

    Abstract : Averaging methods of determining structure, such as X-ray diffraction, do not preserve information about the flexibility of molecules. Cryo-electron tomography allows us to reconstruct individual hydrated objects. READ MORE

  4. 2. Contributions to 3D Image Analysis using Discrete Methods and Fuzzy Techniques : With Focus on Images from Cryo-Electron Tomography

    Author : Magnus Gedda; Ewert Bengtsson; Stina Svensson; Carolina Wählby; Punam Saha; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; digital image analysis; 3D; fuzzy; algorithms; grey-weighted distance; region growing; electron tomography; tracing; fluorescence microscopy; Datoriserad bildanalys; Computerized Image Analysis;

    Abstract : With the emergence of new imaging techniques, researchers are always eager to push the boundaries by examining objects either smaller or further away than what was previously possible. The development of image analysis techniques has greatly helped to introduce objectivity and coherence in measurements and decision making. READ MORE

  5. 3. Revealing the architecture and composition of the sperm flagellum tip

    Author : Davide Zabeo; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Structural biology; Microtubules; Electron microscopy; Cryo-electron microscopy; Cryo-electron tomography;

    Abstract : The eukaryotic flagellum is a membrane-bound protruding organelle with a cytoskeleton of microtubules. Flagella are found in unicellular as well as multicellular organisms, performing a variety of functions. READ MORE

  6. 4. Versatile Association Behavior in Mixtures of Oppositely Charged Amphiphiles : From DNA-Like Assembly of Supramolecular Helices to Coacervation in Chiral Surfactant Systems

    Author : Guanqun Du; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bile salts; Block copolymers; Oppositely charged polymer-surfactant systems; Co-assembly; BS sequestrants; Gemini surfactants; Supramolecular helices; Hexagonal packing; Chirality; Thermoresponsive behavior; Scattering; Tomography; Calorimetry;

    Abstract : As biological surfactants, bile salts (BSs), play important roles in biological processes, i.e., food digestion, but also in BS-related diseases, as well as in applications. READ MORE

  7. 5. Nanoscopic adventures : unraveling macromolecular complexes in infectious diseases via integrative structural biology

    Author : Kai Patric Ehrenbolger; Ronnie Berntsson; Felipe Cava; Jonas Barandun; David Drew; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Infectious diseases; E. faecalis; Microsporidia; Ribosome; Proteasome; Polar Tube; Structural Biology; Single particle Cryo-Electron Microscopy;

    Abstract : This thesis focuses on understanding the underlying molecular mechanisms of infectious diseases, which claim nearly 9 million lives annually. The research centers on critical analysis of pathogen mechanisms and drug resistance. I have mainly focused on two clades of pathogens: Enterococcus faecalis and microsporidia. E. READ MORE