Search for dissertations about: "Crytococcus neoformans"

Found 1 swedish dissertation containing the words Crytococcus neoformans.

2. 1. Development of strategies for construction of thioglycoside building blocks corresponding to repeating triads of Cryptococcus neoformans GXM capsular polysaccharide

   Author : Lina Rydner; Stefan Oscarson; Olof Ramström; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Crytococcus neoformans; Capsular polysaccharide; Thioglycosides; Convergent synthesis; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

   Abstract : This thesis focuses on the development of methods for synthesis of thioglycoside building blocks corresponding to the repeating units of the capsular polysaccharide (CPS) of Cryptococcus neoformans, an opportunistic fungal pathogen. The building blocks are suitable for construction of large synthetic oligosaccharides related to the native CPS-structures which are to be used in biological studies in order to identify protective epitopes with the aim to develop a glycoconjugate vaccine against C. READ MORE