Search for dissertations about: "Cytology"

Showing result 21 - 25 of 173 swedish dissertations containing the word Cytology.

2. 21. Cyclin A1 Expression and Regulation in Hematopoietic and Leukemic Cells

   Author : Jenny Ekberg; Malmö Patologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; General pathology; pathological anatomy; Patologi allmän ; patologisk anatomi; onkologi; Cytologi; cancerology; oncology; Cytology; AML; cyclin A1; apoptosis; cell cycle regulation;

   Abstract : Increased expression of the cell cycle regulatory protein cyclin A1 has previously been detected in patients with acute myeloid leukemia (AML) and targeted overexpression of cyclin A1 in a transgenic mouse model initiated AML. The aim of this thesis was to further study the expression and regulation of cyclin A1 in hematopoietic cells. READ MORE

4. 22. Cytogenetic studies of normal kidney tissue and renal cell carcinoma

   Author : Peter Elfving; Malmö (Abrahamsson) Urologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; Klinisk genetik; Clinical genetics; nonneoplastic kidney tissue; renal cell carcinoma; trisomy 7; Cytogenetics; FISH; oncology; cancerology; Cytologi; onkologi; cancer;

   Abstract : In the present thesis normal kidney tissue and renal cell carcinoma (RCC) were studied by cytogenetic and fluorescence in situ hybridization (FISH) methods to investigate chromosomal aberrations. In the first study, 4 samples of nonneoplastic kidney tissue were cultured for cytogenetic analysis and trisomy 7 was found in all cases in 3-15% of the cells. READ MORE

5. 23. Prognostic factors in soft tissue sarcoma. Tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence

   Author : Jacob Engellau; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth pattern; time-dependence; P-glycoprotein Pgp ; CD44; β-catenin; cyclin A; bcl-2; p53; Ki-67; immunohistochemistry IHC ; whole-tumor sections; tissue microarray TMA ; Soft tissue sarcoma; prognostic factors; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

   Abstract : In adult soft tissue sarcoma (STS) of the extremities and trunk wall, improved prognostic factors are needed to identify patients at high-risk for metastasis. Various factors are included in the many prognostic systems currently in use and the prognostic value of immunohistochemical (IHC) expression of biological markers is unclear. READ MORE

6. 24. Tumors associated with Hereditary Nonpolyposis Colorectal Cancer: Defective Mismatch Repair and Familial Risk of Cancer

   Author : Kajsa Ericson Lindquist; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; cancerology; Cytologi; onkologi; cancer; Multiple Tumors; Hereditary Nonpolyposis Colorectal Cancer; Cytology; Cohort study; Population based; Familial Risk of Cancer; Immunohistochemistry; MSH2; MSH6; MLH1; Microsatellite Instability; Soft Tissue Sarcomas; Cancer of the Upper Urinary Tract; Cancer of the Small Intestine; Colorectal Cancer;

   Abstract : Inactivation of the DNA mismatch repair (MMR) system is a tumorigenic mechanism involved in 15-20% of tumor types such as colorectal and endometrial cancer and is specifically associated with the Hereditary Nonpolyposis Colorectal Cancer (HNPCC) syndrome. These MMR defective tumors are characterized by microsatellite instability (MSI), a phenomenon that reflects alterations in length of repeated sequences, and 90% of MSI tumors show loss of immunohistochemical expression for the MMR protein affected. READ MORE

7. 25. ELDERLY PERSONS LIVING WITH CANCER. Quality of life and lived experience

   Author : Bente Appel Esbensen; Institutionen för hälsovetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytology; Hope; Social network and support; Activities of daily living; Lived experience; Quality of life; Elderly; Cancer; Cytologi; onkologi; cancer; Gerontology; Gerontologi;

   Abstract : Over the coming decades, the numbers of elderly will increase, and through improved lifestyles and better treatment longevity has increased, and with it, the risk of contracting cancer. How elderly people live with cancer has until now attracted limited research. READ MORE