Search for dissertations about: "Cytoreductive"

Showing result 1 - 5 of 18 swedish dissertations containing the word Cytoreductive.

  1. 1. Loco-regional Treatment of Peritoneal Carcinomatosis: Survival, Morbidity and Quality of Life

    Author : Johan Hansson; Haile Mahteme; Wilhelm Graf; Peter Nygren; Peter Naredi; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peritoneal carcinomatosis; Cytoreductive surgery; Intraperitoneal chemotherapy; Survival; SPECT; Morbidity; Mortality; Quality of life; Surgery; Kirurgi; Oncology; onkologi;

    Abstract : Peritoneal carcinomatosis (PC) is traditionally regarded as a terminal stage of disease with a poor prognosis and systemic chemotherapy is regarded as palliative treatment. In order to improve survival and even to achieve cure for selected patients with PC, cytoreductive surgery and intraperitoneal che-motherapy have been advocated. READ MORE

  2. 2. Clinical and Experimental Studies in Peritoneal Metastases from Gastric Cancer

    Author : Bo Hultman; Haile Mahteme; Bruno Walther; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastric cancer; peritoneal metastases; peritoneal carcinomatosis; epidemiology; prognostic factor; survival; neoadjuvant chemotherapy; cytoreductive surgery; HIPEC; health economy; costs; systemic chemotherapy; cultured tumor cells; fluorometric analysis; cancer drug tests; chemo-sensitivity; anti tumor drugs.; Surgery; Kirurgi;

    Abstract : Gastric cancer (GC) is one of leading causes of death in the world, and peritoneal metastases (PM) are a major site of recurrence. PM from GC implies a poor prognosis, with median overall survival (mOS) approximately 3 months and no survival at five years. READ MORE

  3. 3. Pseudomyxoma Peritonei : Aspects of Natural History, Learning Curve, Treatment Outcome and Prognostic Factors

    Author : Håkan Andréasson; Haile Mahteme; Lars Påhlman; Brendan Moran; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseudomyxoma peritonei; Natural history; Learning curve; Cytoreductive surgery; Debulking surgery; Treatment outcome; Prognostic factors; PINCH;

    Abstract : Pseudomyxoma peritonei (PMP) is a rare disease characterized by mucinous peritoneal metastasis (PM). Different loco-regional treatment strategies, i.e. debulking surgery and cytoreductive surgery (CRS) in combination with hyperthermic intraperitoneal chemotherapy (HIPEC), have changed the prognosis for these patients. READ MORE

  4. 4. Operating Room Efficiency and Postoperative Recovery after Major Abdominal Surgery : The Surgical Team’s Efficiency and the Early Postoperative Recovery of Patients with Peritoneal Carcinomatosis

    Author : Erebouni Arakelian; Haile Mahteme; Lena Gunningberg; Jan Larsson; Karin Norlén; Gun Nordström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; efficiency; operating room; postoperative recovery; peritoneal carcinomatos; cytoreductive surgery; HIPEC;

    Abstract : In selected patients, surgical treatments such as cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have enabled curative treatment options for previously incurable diseases, such as peritoneal carcinomatosis (PC). The introduction of resource demanding surgery could affect the work process, efficiency, and productivity within a surgical department and factors influencing patient postoperative recovery processes may have an impact on the efficiency of patient care after major surgery. READ MORE

  5. 5. A Pharmacokinetic and Pharmacodynamic Rationale for Perioperative Cancer Chemotherapy in Patients with Peritoneal Carcinomatosis

    Author : Kurt Van der Speeten; Haile Matheme; Paul Sugarbaker; Lars Pahlman; Ingvar Syk; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peritoneal carcinomatosis; Cytoreductive surgery; Intraperitoneal Chemotherapy; HIPEC; EPIC; Pharmacokinetics; Pharmacodynamics; Morbidity; Mortality; Surgery; Kirurgi; Kirurgi; Surgery;

    Abstract : Peritoneal carcinomatosis (PC) is a common manifestation of both gastrointestinal and gynecologic malignancies. Until recently, this condition was considered beyond curative intent treatment. Since the 1980s, new treatment strategies combining cytoreductive surgery (CRS) with perioperative intraperitoneal and intravenous chemotherapy have emerged. READ MORE