Search for dissertations about: "D-Dimer"

Showing result 1 - 5 of 31 swedish dissertations containing the word D-Dimer.

2. 1. Clinical probability assessment and biochemical markers in the diagnosis of deep vein thrombosis

   Author : Johan Elf; Malmö Klinisk koagulationsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thrombosis; APC-PCI complex.; D-Dimer; Clinical probability; Diagnosis;

   Abstract : The combination of pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the clinical probability assessment was handled by many junior physicians. READ MORE

4. 2. Biomarkers and risk of intracerebral hemorrhage : population-based studies in northern Sweden

   Author : Kristina Johansson; Marcus Lind; Lars Johansson; Jan-Håkan Jansson; Arne Lindgren; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intracerebral hemorrhage; hemorrhagic stroke; factor XII; D-dimer; von Willebrand factor; ABO blood groups; phosphatidylethanol; alcohol; risk markers; biomarkers; Medicine; medicin;

   Abstract : BackgroundIntracerebral hemorrhage (ICH) is a disease associated with a high morbidity and mortality and treatment options for the condition are limited. Even though an ICH event usually comes as a surprise to the affected individual, pathogenetic processes often have occurred before the sudden ICH event and may have preceded disease onset by years. READ MORE

5. 3. On Acute Thrombo-Embolic Occlusion of the Superior Mesenteric Artery

   Author : Stefan Acosta; Martin Björck; Mats Ögren; Bengt Lindblad; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; acute thrombo-embolic occlusion; superior mesenteric artery; intestinal infarction; D-Dimer; intestinal revascularisation; population-based study; incidence; autopsy; Kirurgi; Surgery; Kirurgi;

   Abstract : Acute thrombo-embolic occlusion of the superior mesenteric artery (SMA) with intestinal infarction is a lethal disease, difficult to diagnose in time, with unknown incidence and cause-specific mortality. The aim of this thesis was to characterize the disease and to develop diagnostic methods. READ MORE

6. 4. Factor V Leiden mutation and pregnancy. Haemostasis during pregnancy in non-carriers and carriers of factor V Leiden mutation, with special emphasis on placenta-mediated and venous thromboembolic complications and on blood coagulation and fibrinolysis markers for prediction of complications

   Author : Ulla Kjellberg; Göteborgs universitet; []
   Keywords : Activated protein C; D-dimer; Factor V Leiden; fibrinolysis; haemostasis; obstetric complications; platelet function; pregnancy; prothrombin fragment 1 2; soluble fibrin; Sonoclot; thrombosis;

   Abstract : Factor V Leiden (FVL) mutation elevates the risk of venous thromboembolism (VTE) in general. During pregnancy, the haemostatic balance is changed in the direction of hypercoagulability, resulting in an increased incidence of VTE. 42 women were followed longitudinally during pregnancy and the puerperium. READ MORE

7. 5. High Affinity Synthetic Molecular Binders for Proteins : Design, Synthesis and Evaluation

   Author : Xiaojiao Sun; Lars Baltzer; Thomas Norberg; Ulf Nilsson; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; polypeptide; conjugates; D-dimer; myeloperoxidase; chitinase;

   Abstract : This thesis describes the design and synthesis of small molecule derivatives and their polypeptide conjugates as high affinity binders for proteins: the D-dimer protein (D-dimer), a biomarker for diagnosis of thromboembolic diseases; human myeloperoxidase (MPO), a biomarker for cardiovascular diseases; and chitinases, potential targets for asthma therapy. The interactions between the synthetic binder molecules and those proteins were evaluated by surface plasmon resonance (SPR) biosensor analysis and fluorescence spectroscopy. READ MORE