Search for dissertations about: "D."

Showing result 1 - 5 of 4465 swedish dissertations containing the word D..

  1. 1. On evolution of intracranial changes after severe traumatic brain injury and its impact on clinical outcome

    University dissertation from Umeå : Umeå universitet

    Author : Lukas Bobinski; Lars-Owe Koskinen; Magnus Olivecrona; Peter Lindvall; Marklund Niklas; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe traumatic brain injury; ICP targeted therapy; ICP; decompressive craniectomy; S100B; NSE; cranioplasty; neurokirurgi; Neurosurgery;

    Abstract : Severe traumatic brain injury (sTBI) is a cause of death and disability worldwide and requires treatment at specialized neuro-intensive care units (NICU) with a multimodal monitoring approach. The CT scan imaging supports the monitoring and diagnostics. The level of S100B and neuron specific enolase (NSE) reflects the severity of the injury. READ MORE

  2. 2. Treatment selection in metastatic renal cell carcinoma Towards an individualised approach

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Maria Stenman; Magnus Lindskog; Ulrika Harmenberg; Tim Eisen; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rcc; renal cell carcinoma; kidney cancer; stereotactic radiotherapy; srt; stereotactic body radiotherapy; sbrt; gamma knife radiosurgery; gkrs; stereotactic radiosurgery; srs; radiotherapy; overall survival; prognostic factor; papillary; Oncology; Onkologi;

    Abstract : Renal cell carcinoma (RCC), a common malignancy worldwide, affects 1200 new patients yearly in Sweden. Metastatic RCC (mRCC) develops in one in three and is commonly incurable. Clear cell histology dominates followed by papillary histology. READ MORE

  3. 3. Risk-Adjustment for Swedish In-Hospital Trauma Mortality using International Classification of disease Injury Severity Score (ICISS) issues with description and methods

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Robert Larsen; Folke Sjöberg; Ingrid Steinvall; Mats Fredrikson; Sten M. Walther; Søreide Eldar; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : IntroductionDifferent methods have been used to describe the epidemiology of trauma with varying results. Crude mortality outcome data differ significantly from risk-adjusted information. A previous standard method for risk-adjustment in trauma was the Injury Severity Score (ISS), although it has several shortcomings. READ MORE

  4. 4. Surgically Treated Intracerebral Haemorrhage Pathophysiology and Clinical Aspects

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Lovisa Tobieson; Niklas Marklund; Bijar Ghafouri; Sandro Rossitti; Peter Zsigmond; Jan Hillman; Mikael Svensson; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Mortality and morbidity of intracerebral haemorrhage (ICH) is excessively high, and the case fatality rate has not improved in the last decades. Although surgery for ICH can be life-saving, no positive effect on functional outcome has been found in large cohorts of ICH patients. READ MORE

  5. 5. Interindividual Variability of Drug Transport Proteins Focus on Intestinal Pgp (ABCB1) and BCRP (ABCG2)

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Gunilla Englund; Per Artursson; Håkan Melhus; Andreas Kindmark; Joseph W Polli; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; membrane transport proteins; ATP-Binding Cassette Transporters; P-glycoprotein; Breast Cancer Resistance Protein; Interindividual variability; Galenisk farmaci; PHARMACY Pharmaceutics; FARMACI Galenisk farmaci;

    Abstract : The appearance of adverse drug reactions is a common reason for hospitalization in Western countries. Research on underlying biological mechanisms for interindividual variability in drug response aims to better identify patients with exceptional genetic traits, disease conditions or risk of drug-drug interactions and thereby help to prevent adverse drug reactions. READ MORE