Search for dissertations about: "D1 protein"

Showing result 21 - 25 of 91 swedish dissertations containing the words D1 protein.

  2. 21. Life Style, Molecular Pathology, and Breast Cancer Risk

    Author : Signe Borgquist; Malmö Handkirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hormone receptors; Breast cancer; tissue microarray; histopathology; ERβ; tumour proliferation; cyclin D1; p27; HMG-CoA reductas; life style factors; diet; hormone replacement therapy; obesity; endocrine therapy;

    Abstract : The breast cancer diagnosis covers a wide range of tumours with different geno- and phenotypic characteristics. The diversity among studies on life-style factors and their impact on breast cancer risk might be clarified by recognizing breast cancer as a heterogeneous disease. READ MORE

  4. 22. Structural Plasticity and Function in Cytochrome cd1 Nitrite Reductase

    Author : Tove Sjögren; Christian Cambillau; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; cytochrome cd1; nitrite reductase; oxidase; redox protein; electron transfer; proton transfer; X-ray crystallography; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : Cytochrome cd1 nitrite reductase is a bifunctional enzyme, which catalyses the one-electron reduction of nitrite to nitric oxide, and the four-electron reduction of oxygen to water. The latter is a cytochrome oxidase reaction. Both reactions occur on the d1 haem iron of the enzyme. READ MORE

  5. 23. TISSUE MICROARRAY PERSPECTIVES ON CYCLIN D1 IN BREAST CANCER: Progression, prognosis and prediction

    Author : Karin Jirström; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pathological anatomy; General pathology; tamoxifen resistance; CCND1; Breast cancer; tissue microarrays; Patologi allmän ; patologisk anatomi;

    Abstract : Breast cancer is a truly heterogenous disease, reflected in the existence of a wide spectrum of phenotypic subsets of tumours with varying intrinsic aggressiveness as well as ability to respond to a given treatment. Recent advances in large-scale genomic and proteomic screening techniques have confirmed this heterogeneity also at a molecular level, but there is still a bottleneck to be overcome before the discoveries in the laboratory can be translated into the much more complex clinical situation in order to develop better targeted therapies. READ MORE

  6. 24. Involvement of lipid rafts in G protein-coupled monoamine receptor trafficking and signaling : a pharmacological approach

    Author : Benita Sjögren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The present work focused on lipid raft-mediated modulation of signaling and trafficking of serotonin (5-HT) and dopamine receptors. The 5-HT system is one of the most complex neurotransmitter systems, with a wide distribution both in the CNS and in the periphery. READ MORE

  7. 25. The biological role and clinical impact of SYT-SSX fusion gene and IGF-1R in synovial sarcoma

    Author : Yuntao Xie; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Synovial sarcoma; translocation; SYT-SSX; IGF-1R cyclin D1; cell cycle; proliferation; apoptosis.;

    Abstract : Synovial sarcoma, which is a highly malignant soft tissue tumour occurring mainly in young and middle-aged adults, is characterized by the translocation t(X; 18)(p 11.2; q 11.2). READ MORE