Search for dissertations about: "D2 dopamine receptors"
Showing result 1 - 5 of 86 swedish dissertations containing the words D2 dopamine receptors.
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1. Aerobic fitness and healthy brain aging : cognition, brain structure, and dopamine
Abstract : Background: Performing aerobic exercise and maintaining high levels of aerobic fitness may have positive effects on both brain structure and function in older adults. Despite decades of research however, there is still a rather poor understanding of the neurocognitive mechanisms explaining the positive effects of aerobic exercise on cognition. READ MORE
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2. Dopamine D2 and D3 receptors. Studies on transduction mechanisms and on the role of a D3 gene polymorphism
Abstract : The neurotransmitter dopamine has been implicated in the pathophysiology of, e.g., Parkinson s disease and schizophrenia, and dopamine receptor-active compounds are commonly employed therapeutically in these and other disorders. READ MORE
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3. Up-regulation of dopamine D₂ receptors : in vitro and in vivo studies
Abstract : In the central nervous system (CNS) dopaminergic and dopaminoceptive neurons have the ability to respond to variations in dopamine levels by for example adjusting their dopamine receptor levels. One of the most well known phenomena in this respect is that long-term blockade of D2 receptors with antipsychotic drugs leads to an increase in striatal D2 receptor density of experimental animals as well as of schizophrenic patients as measured in both post-mortem studies and in vivo positron emission tomography studies of brain. READ MORE
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4. The Role of Dopamine-Metabolising Enzymes in Renal Sodium Handling. An Experimental Study in vivo
Abstract : Dopamine (DA) has been shown to act as an intrarenal natriuretic hormone and defects in the renal DA system have been associated with some forms of hypertension. How the DA activity is upregulated durin- increased sodium intake is, however, unknown. READ MORE
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5. Voltage sensitivity of dopamine D2-like receptors
Abstract : G protein coupled receptors (GPCRs) mediate a multitude of responses serving hormonal, neurotransmitter, and sensory functions. These receptors are important drug targets; in fact, about 27 % of prescribed drugs are GPCR ligands. READ MORE