Search for dissertations about: "DBS"

Showing result 1 - 5 of 49 swedish dissertations containing the word DBS.

  2. 1. Capillary driven devices for patient-centric diagnostics

    Author : Gabriel Lenk; Niclas Roxhed; Göran Stemme; Jens Ducrée; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Capillary driven; Microfluidic; Dissolvable valves; PVA; Volume metering; Dried Blood Spots; DBS; Dried Plasma Spots; DPS; Medicinsk teknologi; Medical Technology;

    Abstract : Lateral flow assays is an example of a successful microfluidic platform relying on passive fluid transport, making them suitable for patient-centric and point-of-care applications. Flow control and valving in capillary driven devices typically rely on design-imprinted functions and operations which can be a limiting factor. READ MORE

  4. 2. Dried blood sampling and digital readout to advance molecular diagnostics

    Author : Johan Björkesten; Ulf Landegren; Björn Högberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; molecular diagnostics; dried blood sample; DBS; digital readout; digital enumeration; DNA detection methods; proximity extension assay; protein stability; genotyping; rare mutations; cell free DNA; multiplex protein measurement.; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : A drastically increased capacity to measure large sets of molecular features in numerous patient samples in great detail will be required to fulfill the vision of precision medicine and wellness, which may characterize molecular diagnostics in the 21st century. Also sampling procedures need a renaissance to permit continuous sampling at population levels at reasonable cost. READ MORE

  5. 3. Microelectrode cluster technology for precise interactions with neuronal circuits. Towards highly specific adaptive deep brain stimulation

    Author : Mohsin Mohammed; Neuronano Research Center (NRC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Neuro-electronic interfaceneural interface; neural interface; tissue reactions; deep brain stimulation; Adaptive DBS; biocompatibility; implantation method; neurosurgical tool;

    Abstract : Neuro-electronic interfaces, which can be used for stable communication between neurons-computers over long periods of time, would be valuable for understanding and interacting with the nervous system. A major challenge has been to overcome the tissue reactions towards implanted electrodes. READ MORE

  6. 4. Deep brain stimulation in obsessive-compulsive disorder

    Author : Matilda Naesström; Owe Bodlund; Patric Blomstedt; Johan Eriksson; Lotta M. J. Strömsten; Ellinor Salander Renberg; Keith Matthews; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; deep brain stimulation DBS ; obsessive-compulsive disorder OCD ; psykiatri; Psychiatry;

    Abstract : Deep brain stimulation (DBS) is under investigation for severe obsessive-compulsive disorder (OCD) resistant to other therapies. As a crucial part of the anxiety circuit in the brain, the bed nucleus of stria terminalis (BNST) has been proposed as a target for DBS in OCD. READ MORE

  7. 5. Computational Models in Deep Brain Stimulation : Patient‐Specific Simulations, Tractography, and Group Analysis

    Author : Teresa Nordin; Karin Wårdell; Simone Hemm-Ode; Johannes D. Johansson; Harith Akram; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Anisotropy; Deep brain stimulation DBS ; Finite element method FEM ; Patient‐specific simulation; Probabilistic stimulation maps PSM ; Tractography;

    Abstract : Deep brain stimulation (DBS) is an established method for symptom relief in movement disorders like Parkinson’s disease, essential tremor (ET), and dystonia. The therapy is based on implanting an electrode with four contacts in the deep brain structures where it provides electrical stimulation, mainly impacting the nerve tracts. READ MORE