Search for dissertations about: "DILI"

Showing result 6 - 9 of 9 swedish dissertations containing the word DILI.

  2. 6. Optimization of HIV and tuberculosis co-treatment in Tanzania : drug-drug interactions and clinical outcomes

    Author : Sabina Mugusi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HIV;

    Abstract : Background: Sub-Saharan Africa has been greatly affected by the HIV epidemic, with an estimated 23.5 million people living with HIV/AIDS (PLWHA) residing within this region by the end of 2011, being the leading course of morbidity and mortality. Tanzania is one of the countries in this region with an HIV prevalence of 5.7% i. READ MORE

  4. 7. Array-based identification of disease-associated proteins

    Author : Maria Mikus; Peter Nilsson; Jochen M. Schwenk; Ina Schuppe-Koistinen; Dolores Cahill; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affinity proteomics; Antibody array; Antigen array; Amyotrophic lateral sclerosis; Asthma; Atopic dermatitis; Biomarker discovery; Drug-induced liver injury; Microarray; Plasma; Protein microarray; Protein profiling; Serum; Suspension bead array; Bioteknologi; Biotechnology;

    Abstract : To increase our understanding of the human body in both health and disease, proteins can be studied in samples such as plasma and serum to provide a molecular profile of the physiological status. In the work presented in this thesis, array-based methods were used to study associations of protein and autoantibody profiles with disease. READ MORE

  5. 8. Pharmacokinetic and pharmacogenetic aspects of drug-drug interactions between antiretroviral and anti-tuberculosis drugs in Ethiopian patients : implication for optimization of TB-HIV co-treatment

    Author : Abiy Habtewolde Eyakem; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : TB and HIV are immuno-pathologically interacting epidemic infectious diseases affecting the lives of millions globally & sub-Saharan African region accounts the highest burden of both diseases. Although effective therapies are available for the management of each, TB-HIV co-treatment has faced challenges mainly due to drug-drug interactions & overlapping drug toxicities. READ MORE

  6. 9. Non-Invasive Characterization of Liver Disease : By Multimodal Quantitative Magnetic Resonance

    Author : Markus Karlsson; Peter Lundberg; Gunnar Cedersund; Nils Dahlström; Stergios Kechagias; Steven Sourbron; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : There is a large and unmet need for diagnostic tool that can be used to characterize chronic liver diseases (CLD). In the earlier stages of CLD, much of the diagnostics involves performing biopsies, which are evaluated by a histopathologist for the presence of e.g. fat, iron, inflammation, and fibrosis. READ MORE