Search for dissertations about: "DISSERTATION ON ASTHMA and copd"

Found 5 swedish dissertations containing the words DISSERTATION ON ASTHMA and copd.

  2. 1. On causes and regulation of anti-viral defence in asthma and COPD

    Author : Mandy Menzel; Respiratorisk immunofarmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; asthma; chronic obstructive pulmonary disease; rhinovirus; exacerbation; airway epithelial cell; ; pattern recognition receptors; interferon; allergen; azithromycin; inflammasome; epithelial-derived cytokines; oxidative stress; asthma; chronic obstructive pulmonary disease; rhinovirus; exacerbation; airway epithelial cell; pattern recognition receptors; interferon; allergen; azithromycin; inflammasome; epithelial-derived cytokines; oxidative stress;

    Abstract : Rhinovirus infection is a main trigger of asthma and COPD exacerbations. dsRNA, a viral replication intermediate, is sensed by pattern recognition receptors in the airway epithelium leading to down-stream induction of anti-viral interferons. READ MORE

  4. 2. Serine protease inhibitors in the upper and lower airways

    Author : Camilla Hollander; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; auditive system and speech; Neutrophils; audiology; Otorhinolaryngology; Medicin människa och djur ; AAT; Medicine human and vertebrates ; SLPI; cytokines chemokines; anti-proteases; audiologi; hörsel- och talorganen; Airway inflammation; Otorinolaryngologi;

    Abstract : Proteases and their inhibitors are implicated in the physiology and pathology of the airways. Protease inhibitors include those produced locally, such as secretory leukocyte protease inhibitor (SLPI), and those produced mainly by the liver that can reach the airways via passive diffusion, such as alpha1-antitrypsin (AAT). READ MORE

  5. 3. New aspects of tissue mast cells in inflammatory airway diseases

    Author : Cecilia Andersson; Luftvägsinflammation; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Mast cell are found throughout the body, but are especially prominent in tissues that have direct contact with the external milieu such as the skin, gastrointestinal tract and lungs. Mast cells are commonly recognized for their detrimental role in allergic reactions and can, upon activation through the high-affinity receptor for IgE (FcεRI), rapidly produce and secrete many of the mediators responsible for the typical symptoms in urticaria, asthma and rhinitis. READ MORE

  6. 4. Targeting viral induced TSLP - an airway treatment opportunity

    Author : Angelica Brandelius; Respiratorisk immunofarmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Respiratory viral infections cause exacerbations of asthma and COPD that cannot be effectively treated today. Thymic Stromal Lymphopoietin (TSLP) is an upstream epithelial cytokine linking the innate and adaptive immune system. Viral stimuli induce epithelial overexpression of TSLP in asthma and COPD. READ MORE

  7. 5. Mechanisms of inflammatory signalling in chronic lung diseases : transcriptomics and metabolomics approaches

    Author : Bettina Levänen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Sarcoidosis, asthma and chronic obstructive pulmonary disease (COPD) are inflammatory pulmonary diseases with many different clinical phenotypes. A central characteristic of all three diseases is the altered airway function due to inflammation. READ MORE