Search for dissertations about: "DLG2"

Found 4 swedish dissertations containing the word DLG2.

  2. 1. MOLECULAR AND GENETIC STUDIES OF DLG2 IN NEUROBLASTOMA AND COLORECTAL CANCER

    Author : Simon Keane; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Neural crest; Neuroblastoma; colon cancer; DLG2; MYCN; LIN7A; inflammation;

    Abstract : Neuroblastoma is one of the most common extra cranial solid tumors in children. It is one of the most common causes of death amongst the pediatric malignancies. READ MORE

  4. 2. Anaplastic lymphoma kinase activity, a therapeutic target, suppresses neuroblastoma cell differentiation

    Author : Joachim T. Siaw; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; ALK; 11q.; DLG2; SP1; differentiation; crizotinib; ceritinib; brigatinib;

    Abstract : Neuroblastoma (NB) is the most common extracranial pediatric solid malignancy caused by the failed differentiation of precursor cells of the developing sympathetic nervous system. NB accounts for about 15% of childhood cancer-related deaths. READ MORE

  5. 3. Interaction of genetic and environmental factors in childhood asthma and allergy

    Author : Anna Gref; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Asthma and allergy are the most common chronic childhood diseases. Their occurrences are influenced by both genetic and environmental factors, although the underlying mechanisms are not fully understood. READ MORE

  6. 4. Genomic instability and genetic heterogeneity in neuroblastoma tumours

    Author : Niloufar Javanmardi; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma tumour; subclone; mutation; relapse; deep sequencing; tumour supressor gene;

    Abstract : Neuroblastoma (NB), a tumour of the sympathetic nervous system and the most common malignant disease of early childhood, is responsible for 9% of paediatric cancer related deaths. Aggressive NB still constitutes a major clinical problem with survival rates of about 35%. READ MORE