Search for dissertations about: "DN"

Showing result 1 - 5 of 54 swedish dissertations containing the word DN.

  2. 1. Rates and patterns of molecular evolution in avian genomes

    Author : Paulina Bolívar; Hans Ellegren; Carina F. Mugal; Mikkel Heide Schierup; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Molecular evolution; recombination; GC-biased gene conversion; Hill-Robertson interference; effective population size; dN dS; distribution of fitness effects; avian genomes; collared flycatcher; sex chromosomes; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : Evolution is the change in inherited characteristics of a population through subsequent generations. The interplay of several evolutionary mechanisms determines the rate at which this change occurs. READ MORE

  4. 2. Identification of the susceptibility genes in type 1 diabetes and diabetic nephropathy

    Author : Jun Ma; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Type 1 Diabetes; Diabetic Nephropathy; Genetic Association; Single Nucleotide Polymorphism;

    Abstract : Genetic susceptibility plays an important role in the pathogenesis of type 1 diabetes (T1D) and diabetic nephropathy (DN). The present study aims to investigate the association between single nucleotide polymorphisms (SNPs) in candidate genes and DN. READ MORE

  5. 3. Genetic and functional analyses of diabetic nephropathy with focus on chromosome 3q

    Author : Dongying Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Diabetic nephropathy; chromosome 3; single nucleotide polymorphism; genetic association; gene expression;

    Abstract : Diabetic nephropathy (DN) is a complex disease affected by both genetic and environmental factors. Genetic and functional analyses of the susceptibility and/or resistance genes in DN may provide useful information for better understanding the pathogenesis and further developing novel therapeutic approaches in this disease. READ MORE

  6. 4. Searching for new biomarkers of diabetic nephropathy in Malaysian subjects with type 2 diabetes

    Author : Norhashimah Abu Seman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : According to the latest National Health and Morbidity Survey reports in year 2011, the prevalence of type 2 diabetes (T2D) in Malaysia has risen to 20.8%, much faster than expected. Of concern, 57% of T2D patients in Malaysia had diabetic nephropathy (DN). READ MORE

  7. 5. Factors influencing the risk of diabetic nephropathy : analyses of genes, smoking and diet

    Author : Anna Möllsten; Gisela Dahlquist; Lise Tarnow; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1 diabetes; diabetic nephropathy; oxidative stress; smoking; diet; blood pressure; renin-angiotensin system; nitric oxide synthase; Kidney diseases; Njursjukdomar;

    Abstract : Diabetic long-term complications, despite intensive treatment, cause serious handicaps at relatively young age in diabetic patients. Diabetic nephropathy (DN) develops in up to 30% of patients with type 1 diabetes (T1D). READ MORE