Search for dissertations about: "DNA CONTENT"

Showing result 1 - 5 of 224 swedish dissertations containing the words DNA CONTENT.

  2. 1. DNA-Controlled Lipid-Membrane Fusion

    Author : Lisa Simonsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; exocytosis; vesicles; DNA; FRET; fluorescence resonance energy transfer; model system; total internal reflection fluorescence microscopy; TIRF microscopy; self-assembly; site-specificity; diffusion; biomembranes; lipid bilayer; membrane fusion;

    Abstract : Membrane fusion is essential for nerve-cell communication, for protein transport between cell organelles and the cell-membrane and for enabling the merger between virus and host membranes during virus infection. We have demonstrated that short DNA oligonucleotides, membrane-attached via CH in an orientation that mimics the overall zipperlike architecture of fusion-inducing proteins, induce fusion of both suspended vesicles and vesicles site-specifically tethered to SLBs. READ MORE

  4. 2. DNA Analysis of PCR-Inhibitory Forensic Samples

    Author : Johannes Hedman; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; amylase; statistical modelling; principal components analysis; PCR inhibitors; PCR inhibition; forensic DNA analysis; DNA polymerase blend; DNA polymerase; crime scene samples;

    Abstract : DNA evidence, linking perpetrators to crime scenes, is central to many legal proceedings. However, crime scene samples often contain extraneous substances that may interfere with the PCR-based forensic analysis, resulting in partial or negative DNA profiles. Extensive DNA purification may remove inhibitors, but involves the risk of DNA loss. READ MORE

  5. 3. Overstretching short DNA – Single-molecule force spectroscopy studies

    Author : Niklas Bosaeus; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA stretching; mechanical properties of DNA; single molecule; optical tweezers; DNA structure;

    Abstract : Structural deformation of DNA has a central role in many biological processes. It occurs, for example, during replication, transcription, and regulation of the activity of the genome. To understand these fundamental processes it is necessary to have a detailed knowledge of the mechanical properties of DNA. READ MORE

  6. 4. Salivary gland neoplasms : studies on the cytoskeleton, the secretory apparatus and the nuclear DNA content

    Author : Hans Gustafsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Salivary gland neoplasms; intermediate filaments; immuno- histochemistry; ultrastructure; DNA; development; histogenesis; progno¬sis;

    Abstract : The heterogeneity of salivary gland neoplasms have made classification and prognostication of these tumours sometimes difficult, and the in­troduction of techniques, such as enzyme and carbohydrate histochemis­try and electron microscopy have only to a certain extent increased our knowledge in these respects. In the present study immunohistochemical methods have been used to identify intermediate filament proteins (IFP) in normal fetal and adult parotid glands, as well as in salivary neo­plasms. READ MORE

  7. 5. Concentrated DNA-amphiphiles Structure, Hydration, and Dynamics

    Author : Cecilia Leal; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; amphiphiles; DNA; Physical chemistry; diffusion NMR; solid-state NMR; electrostatics; dynamics; local order; Fysikalisk kemi; hydration;

    Abstract : The structure, hydration, and dynamics of concentrated DNA-amphiphile complexes were investigated by small-angle X-ray diffraction, sorption calorimetry, and nuclear magnetic resonance. A concentrated, electroneutral, DNA-amphiphile complex can be formed by mixing charge-stoichiometric solutions. READ MORE