Search for dissertations about: "DNA arrays"

Showing result 16 - 20 of 78 swedish dissertations containing the words DNA arrays.

  2. 16. DNA methylation as a prognostic marker in clear cell Renal Cell Carcinoma

    Author : Emma Andersson-Evelönn; Sofie Degerman; Magnus Hultdin; Göran Roos; Börje Ljungberg; Ralph Peeker; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clear cell renal cell carcinoma; DNA methylation; Prognosis; Clinical outcome; Epigenetic classifiers;

    Abstract : Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cell carcinoma worldwide. Metastatic ccRCC is correlated to poor prognosis whereas non-metastatic disease has a 5-year survival rate up to 90%. READ MORE

  4. 17. Methods and applications in DNA sequence alignments

    Author : Ellen Sherwood; Karolinska Institutet; Karolinska Institutet; []
    Keywords : DNA sequence alignment; CNV; Chicken; Trypanosoma cruzi.;

    Abstract : DNA sequence alignment is one of the most common bioinformatics tasks. Alignment analysis for eukaryotic genomes is challenging because the datasets are large. Repeat sequences also make the analysis difficult. This thesis describes new methods which we have developed for DNA sequence alignment that address these problems. READ MORE

  5. 18. Repetitive DNA in search of a function - a study of telomeric and centromeric sequences in Chironomus

    Author : Casimiro Castillejo-Lopez; Udo Häckers grupp Utvecklingsbiologi i invertebrater; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chironomus; CENP-B box; mobile elements; reverse transcriptase; gene conversion; satellite; repetitive DNA; Telomere; centromere; Genetics; cytogenetics; Genetik; cytogenetik;

    Abstract : Repetitive DNA is quantitatively the main component of telomeres and centromeres, structures responsible for maintenance of the eukaryotic chromosome. The telomere is the specialized nucleoprotein complex that terminates linear chromosomes. READ MORE

  6. 19. Modelling Allelic and DNA Copy Number Variations using Continuous-index Hidden Markov Models

    Author : Susann Stjernqvist; Matematisk statistik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hidden Markov models; DNA copy number; allelic copy number; Markov chain Monte Carlo;

    Abstract : In human cells there are usually two copies of each chromosome, but in cancer cells abnormalities could exist. The differences consist of segments of chromosomes with an altered number of copies. There can be deletions as well as amplifications and the lengths of the segments can also vary. READ MORE

  7. 20. DNA topoisomerases and nucleosome dynamics in fission yeast

    Author : Ulrika Norman Axelsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The organization of DNA and associated proteins into chromatin allows for compaction and protection of large eukaryotic genomes. However, it also poses a challenge to fundamental cellular processes such as DNA replication, recombination, repair and transcription. READ MORE