Search for dissertations about: "DNA base analogs"
Found 5 swedish dissertations containing the words DNA base analogs.
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1. Fluorescence Probing of DNA Structures in Biology and Nanotechnology
Abstract : Much has been learnt about DNA since its structure was discovered about half a century ago. Scientists everlasting urge to look beyond and deeper into the intricate machinery of life, has continuously pushed technology forward. READ MORE
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2. Fluorescent DNA Modifications for Use as Probes of Biological Structure and as Nanotechnological Functional Units
Abstract : .... READ MORE
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3. Intelligent Nucleic Acid Interactions with Peptide Nucleic Acid (PNA) and Recombination Enzyme RecA
Abstract : The work presented in this thesis focuses on interactions between nucleic-acids in biological systems, particularly interactions of the promising drug-candidate peptide nucleic acid (PNA), and on protein-DNA intermediates during recombination. Several experimental techniques, mainly circular dichroism and fluorescence spectroscopy, have been used to characterize the interactions of interest. READ MORE
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4. DNA analogs for the purpose of gene therapy
Abstract : This thesis describes DNA analogs and their potential use for gene therapeutic purposes, primarily by sequence specific strand-invasion of double-stranded DNA. Gene therapy is classically thought of as restoration of a defect gene. READ MORE
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5. Crystal structures of human deoxyribonucleotidases
Abstract : Human 5’-deoxyribonucleotidases are ubiquitous enzymes that catalyze the dephosphorylation of deoxyribonucleoside monophosphates to their nucleoside form. They participate in the regulation of deoxyribonucleotide pools and protect DNA replication from inbalance of precursors. READ MORE