Search for dissertations about: "DNA double strand-breaks"
Showing result 1 - 5 of 73 swedish dissertations containing the words DNA double strand-breaks.
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1. Ionising radiation and DNA double strand breaks in human cells : formation, intracellular protection and consequences
Abstract : .... READ MORE
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2. Recognition and signaling of DNA double-strand breaks in human cells
Abstract : DNA double-strand breaks (DSBs) are the most toxic type of DNA damage. Fortunately, our cells have highly conserved pathways that detect and repair DSBs. Defects in DSB signaling and DSB repair pathways result in genomic instability that predisposes for cancer development. READ MORE
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3. Role of Non-Homologous End-Joining in Repair of Radiation-Induced DNA Double-Strand Breaks
Abstract : Efficient and correct repair of DNA damage, especially DNA double-strand breaks (DSBs), is vital for the survival of individual cells and organisms. Defects in the DNA repair may lead to cell death or genomic instability and development of cancer. READ MORE
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4. Replication Dynamics in the DNA Damage Response
Abstract : Faithful DNA replication is essential and the induction of replication stress may have profound effects on genomic integrity. This is demonstrated by the formation of DNA double strand breaks (DSBs), considered to be the most toxic DNA lesions, at stalled replication forks. READ MORE
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5. Characterization of Budding Yeast Nonhomologous End-Joining at DNA Double-Strand Breaks and Telomeres
Abstract : The yeast K. lactis efficiently integrates DNA by illegitimate recombination (IR). IR was completely dependent upon nonhomologous end-joining (NHEJ). In contrast to S. READ MORE