Search for dissertations about: "DNA homology"

Showing result 1 - 5 of 68 swedish dissertations containing the words DNA homology.

  2. 1. Bacterial DNA repair and molecular search

    Author : Arvid H. Gynnå; Johan Elf; Stephen Kowalczykowski; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA repair; DNA damage; homologous recombination; homologous repair; recombination; RecA; I-SceI; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : Surveillance and repair of DNA damage is necessary in all kinds of life. Different types of DNA damage require different repair mechanisms, but these mechanisms are often similar in all domains of life. The most serious type of damage, double stranded DNA breaks, are for example repaired in conceptually similar ways in both bacteria and eukaryotes. READ MORE

  4. 2. DNA in centromeres of Chironomus pallidivittatus

    Author : Ching Liao; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Genetics; Chironomus; CEN DNA; transposable element; centromere; repetitive DNA; cytogenetics; Genetik; cytogenetik;

    Abstract : The centromeres of most higher eukaryotes are embedded within large regions of constitutive heterochromatin and consist of large quantities of highly repetitive DNA. Transposable elements are also found in these regions. READ MORE

  5. 3. Dynamics of the Bacterial Genome : Rates and Mechanisms of Mutation

    Author : Sanna Koskiniemi; Dan Andersson; Diarmaid Hughes; Ivan Matic; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteria; bacterial evolution; genome reduction; gene loss; serial passage; DNA homology; tranlesion DNA polymerase; stress; Microbiology; Mikrobiologi; Bacteriology; Bakteriologi; Evolutionary Genetics; Evolutionär genetik; Mikrobiologi; Microbiology;

    Abstract : Bacterial chromosomes are highly dynamic, continuously changing with respect to gene content and size via a number of processes, including deletions that result in gene loss. How deletions form and at what rates has been the focus of this thesis. In paper II we investigated how chromosomal location affects chromosomal deletion rates in S. READ MORE

  6. 4. Unveiling Mechanistic Details of Macromolecular Interactions: Structural Design and Molecular Modelling of DNA-Protein Systems in Their Active State

    Author : Anna Reymer; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molecular modelling; intercalation; homologous recombination; DNA; ruthenium II polypyridyl compounds; human Rad51;

    Abstract : Molecular structure is fundamental for understanding mechanisms of molecular interactions. This applies not least to understanding biological function: every biological cell, whether bacterial or human, is an immensely complex system of thousands of molecules that exist in constant motion and interaction with each other. READ MORE

  7. 5. Mechanisms and DNA Specificity in Site-specific Recombination of Integron Cassettes

    Author : Carolina Johansson; Lars Sundström; Dan Andersson; Didier Mazel; Uppsala universitet; []
    Keywords : Microbiology; lateral gene transfer; site-specific recombination; tyrosine recombinase; integron; single-stranded; DNA hairpin; Mikrobiologi; farmaceutisk mikrobiologi; Pharmaceutical Microbiology;

    Abstract : Bacterial resistance to antibiotics has become a serious problem. This is due to the remarkable ability of bacteria to respond and rapidly adapt to environmental changes. Integrons are elements with the capacity for gene capture by an integron-encoded site-specific recombinase called IntI. READ MORE