Search for dissertations about: "DNA in crime"

Showing result 1 - 5 of 10 swedish dissertations containing the words DNA in crime.

2. 1. DNA Analysis of PCR-Inhibitory Forensic Samples

   Author : Johannes Hedman; Teknisk mikrobiologi; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; amylase; statistical modelling; principal components analysis; PCR inhibitors; PCR inhibition; forensic DNA analysis; DNA polymerase blend; DNA polymerase; crime scene samples;

   Abstract : DNA evidence, linking perpetrators to crime scenes, is central to many legal proceedings. However, crime scene samples often contain extraneous substances that may interfere with the PCR-based forensic analysis, resulting in partial or negative DNA profiles. Extensive DNA purification may remove inhibitors, but involves the risk of DNA loss. READ MORE

4. 2. Sensitive Forensic DNA Analysis : Application of Pyrosequencing and Real-time PCR Quantification

   Author : Hanna Andréasson; Marie Allen; Ulf Gyllensten; Pål Nyrén; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; forensic; sensitive DNA analysis; DNA quantification; mtDNA; Real-time PCR; Pyrosequencing; Genetik; Clinical genetics; Klinisk genetik;

   Abstract : The field of forensic genetics is growing fast and the development and optimisation of more sensitive, faster and more discriminating forensic DNA analysis methods is highly important. In this thesis, an evaluation of the use of novel DNA technologies and the development of specific applications for use in forensic casework investigations are presented. READ MORE

5. 3. PCR inhibition mechanisms in forensic DNA analysis

   Author : Maja Sidstedt; Teknisk mikrobiologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; PCR inhibition mechanisms; Real-time PCR; Digital PCR; Massively parallel sequencing;

   Abstract : In forensic DNA analysis, the polymerase chain reaction (PCR) enables DNAanalysis of minute biological crime scene traces. PCR is an enzymatic reaction for amplification of specific DNA fragments involving both biochemical andbiophysical processes. The main analytical challenge is posed by the nature of the samples of interest. READ MORE

6. 4. Bayesian inference for detection problems in biology

   Author : Ronny Hedell; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PCR; Bayesian inference; Forensic DNA analysis; Syndromic surveillance; Bacillus anthracis; Markov chain Monte Carlo; Allele dropout; Bacillus anthracis;

   Abstract : This thesis is about different kinds of detection problems in biology: detection of DNA sequences in crime scene samples, detection of harmful bacteria in feed and food stuff and detection of epidemical diseases in animal populations. In each case, biological data is produced or collected in order to determine which DNA sequences, bacteria types or diseases are present, if any. READ MORE

7. 5. Populations and Statistics in Forensic Genetics

   Author : Andreas Tillmar; Bertil Lindblom; Gunilla Holmlund; Petter Mostad; Peter de Knijff; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : DNA has become a powerful forensic tool for solving cases such as linking a suspect to a crime scene, resolving biological relationship issues and identifying disaster victims. Traditionally, DNA investigations mainly involve two steps; the establishment of DNA profiles from biological samples and the interpreta-tion of the evidential weight given by theses DNA profiles. READ MORE