Search for dissertations about: "DNA methods trends"

Showing result 1 - 5 of 7 swedish dissertations containing the words DNA methods trends.

  2. 1. Empirical Bayes Methods for DNA Microarray Data

    Author : Ingrid Lönnstedt; Allan Gut; Tom Britton; Mette Langaas; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mathematical statistics; two-channel microarrays; differential expression; replication; empirical Bayes; factorial design; interaction; time trends; hierarchical Bayes; MCMC simulations; ANOVA; F-statistics; Matematisk statistik; Mathematical statistics; Matematisk statistik;

    Abstract : cDNA microarrays is one of the first high-throughput gene expression technologies that has emerged within molecular biology for the purpose of functional genomics. cDNA microarrays compare the gene expression levels between cell samples, for thousands of genes simultaneously. READ MORE

  4. 2. Improved Techniques for High-Throughput Molecular Diagnostics

    Author : Mario Curcio; KTH; []
    Keywords : DNA; Molecular Diagnostics;

    Abstract : The amount of information derived from sequencing the humangenome is leading to an exponential increase in the rate atwhich genes and genetic disorders are mapped and characterized.As a consequence, the demand for genetic testing is alsodramatically increasing. READ MORE

  5. 3. Deciphering sequence data : A multivariate approach

    Author : Maria Sandberg Hiltunen; Michael Sjöström; Svante Wold; Lars Ståhle; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Principal properties; amino acids; nucleotides; tRNA; DNA; multivariate data analysis; sequence analysis; QSAR; quantitative sequence activity relationships;

    Abstract : In this thesis, attention has been focused on the quantitative description of nucleic acids, proteins and peptides. The strategy was to use multivariate chemometrical methods for improving the understanding of the complex structural codes of these kinds of biological molecules. READ MORE

  6. 4. Latent variable based computational methods for applications in life sciences : Analysis and integration of omics data sets

    Author : Max Bylesjö; Johan Trygg; Tormod Naes; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; orthogonal projections to latent structures; OPLS; O2PLS; K-OPLS; kernel-based; non-linear; regression; classification; Populus; Chemistry; Kemi;

    Abstract : With the increasing availability of high-throughput systems for parallel monitoring of multiple variables, e.g. levels of large numbers of transcripts in functional genomics experiments, massive amounts of data are being collected even from single experiments. READ MORE

  7. 5. Molecular methods in malaria control in the era of pre-elimination

    Author : Ulrika Morris; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Increased funding combined with effective malaria control methods for prevention, diagnosis, and treatment, has resulted in a 30% reduction of the global malaria burden over the last decade. As malaria prevalence declines in areas of successful malaria control, the proportion of subpatent infections that fall below the detection level of malaria rapid diagnostic tests (RDTs) and microscopy increases. READ MORE