Search for dissertations about: "DNA nano"
Showing result 1 - 5 of 49 swedish dissertations containing the words DNA nano.
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1. Single DNA Molecule Analysis – New Tools for Medical Diagnosis
Abstract : The DNA molecule, the blueprint of life, contains an enormous amount of information. The information is coded by the combination of four bases; adenine, cytosine, guanine, and thymine, that, together with the sugar-phosphate backbones, make up the DNA double helix. READ MORE
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2. Microfluidic Preparation and Transport of Long DNA using Pillar Arrays
Abstract : This thesis presents a set of microfluidic tools and experimental studies for preparing (> 20 kbp) for genetic analysisas well as the transport of high-concentration, long-DNA solutions in pillar arrays.Long-DNA sample preparation with conventional gel-based techniques is slow (tens of hours to days) and laborious. READ MORE
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3. Silicon Nanopore Arrays : Fabrication and Applications for DNA Sensing
Abstract : Nanopore biomolecule sensing and sequencing has emerged as a simple but powerful tool for single molecule studies over the past two decades. By elec- trophoretically driving single molecules through a nanometer-sized pore, often sitting in an insulating membrane that separates two buffer solutions, ionic current blockades can be detected to reveal rich information of the molecules, such as DNA length, protein size and conformation, even nucleic acid se- quence. READ MORE
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4. Competitive-Binding Based Optical DNA Mapping - From Bacterial Plasmids to the Human Genome
Abstract : Significant advances within the field of DNA sequencing have allowed us to study DNA at a level of detail that was previously impossible. However, dynamic genomic regions with a high degree of structural variations, while being linked to disease in humans and increased resistance to antibiotics, are still challenging to characterize. READ MORE
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5. Development of methods for optical mapping of nanoconfined DNA
Abstract : .... READ MORE