Search for dissertations about: "DNA polymerases"
Showing result 1 - 5 of 35 swedish dissertations containing the words DNA polymerases.
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1. The consequences of DNA lesions for mitochondrial DNA maintenance
Abstract : Eukaryotic cells have their own energy-producing organelles called mitochondria. The energy is stored in the adenosine triphosphate (ATP) molecule and is produced via the oxidative phosphorylation process inside the mitochondria. Thirteen of the essential proteins required for this process are encoded on the mitochondrial DNA (mtDNA). READ MORE
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2. Ribonucleotides in DNA - Application in genome-wide DNA polymerase tracking and physiological role in eukaryotes
Abstract : The genetic code in the eukaryotic cell is stored in the form of DNA, which is more resistant to hydrolysis than RNA. Replication fidelity and DNA repair mechanisms are in place to ensure genomic integrity to preserve the information encoded. READ MORE
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3. DNA Analysis of PCR-Inhibitory Forensic Samples
Abstract : DNA evidence, linking perpetrators to crime scenes, is central to many legal proceedings. However, crime scene samples often contain extraneous substances that may interfere with the PCR-based forensic analysis, resulting in partial or negative DNA profiles. Extensive DNA purification may remove inhibitors, but involves the risk of DNA loss. READ MORE
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4. Structure of eukaryotic DNA polymerase epsilon and lesion bypass capability
Abstract : To transfer the information in the genome from mother cell to daughter cell, the DNA replication must be carried out only once and with very high fidelity prior to every cell division. In yeast there are several different DNA polymerases involved in DNA replication and/or DNA repair. READ MORE
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5. Role of yeast DNA polymerase epsilon during DNA replication
Abstract : Each cell division, the nuclear DNA must be replicated efficiently and with high accuracy to avoid mutations which can have an effect on cell function. There are three replicative DNA polymerases essential for the synthesis of DNA during replication in eukaryotic cells. READ MORE