Search for dissertations about: "DNA structure"

Showing result 6 - 10 of 574 swedish dissertations containing the words DNA structure.

  2. 6. Fluorescence Probing of DNA Structures in Biology and Nanotechnology

    Author : Peter Sandin; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA; Fluorescent DNA base analog; UV‐Vis spectroscopy; DNA nanostructure; self‐assembly; time‐resolved fluorescence spectroscopy;

    Abstract : Much has been learnt about DNA since its structure was discovered about half a century ago. Scientists everlasting urge to look beyond and deeper into the intricate machinery of life, has continuously pushed technology forward. READ MORE

  4. 7. Association of Amphiphiles and Polyelectrolytes with DNA

    Author : Yulia S Mel'nikova; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; cryo-TEM; SAXS; fluorescence microscopy; DNA condensation; DNA-polyelectrolyte; DNA- amphiphile interactions; Fysikalisk kemi;

    Abstract : DNA- cationic amphiphile and DNA-cationic polymer systems were studied with respect to the intermolecular interactions, as well as structure and stability of formed complexes. The thesis is divided in two parts: one section is a summary and the other section contains five papers. READ MORE

  5. 8. Controlling DNA compaction and the interaction with model biomembranes

    Author : Marie-Louise Ainalem; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; model biomembrane; DNA compaction; cryo-TEM; null ellipsometry; dynamic light scattering; toroid; bilayer; neutron reflectivity; dendrimer; PAMAM; DNA; poly amido amine ;

    Abstract : The studies described in this thesis forms part of a larger collaborative project, Neonuclei, with the objective to design a module for packaging the negatively charged DNA into a ”neonucleus” with transcription competence. There are many applications that require control of DNA compaction, i.e. packaging or condensation. READ MORE

  6. 9. Structural Adaptation of DNA to Small Ligands and Recombination Proteins

    Author : Hye-Kyung Kim; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; triplex DNA; groove binders; intercalators; SANS; DNA; optical spectroscopy; recombination proteins;

    Abstract : In order to contribute to the understanding of mechanisms of recognition in nucleic acid systems, the interaction of DNA with a variety of ligands, representing different cases of adaptation of the double-helix structure, was studied using flow linear dichroism (LD), circular dichroism (CD), fluorescence and absorption spectroscopic techniques. A chiral hydrophobic metal complex, [Ru(dpphen)3]2+ was examined, since this had been reported to be the most efficient molecule to discriminate DNA handedness. READ MORE

  7. 10. Fixation of Functionalized DNA Nanostructures

    Author : Erik Lundberg; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; triplex recognition; dna; self-assembly; gel electrophoresis; nanotechnology; cross-linking; spectroscopy; fixation; fret; click chemistry;

    Abstract : This thesis features results from two different studies on a fully addressable non-repetitive network on the nanometre scale, assembled by synthetic DNA molecules. A bio-inspired molecular approach, based on principles of self-assembly, has brought about a paradigm shift in nanoscience, from a top-down to a bottom-up perspective. READ MORE