Search for dissertations about: "DNA synthesis"
Showing result 21 - 25 of 356 swedish dissertations containing the words DNA synthesis.
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21. Initiation of Mammalian Mitochondrial DNA Replication
Abstract : Mitochondria produce most of the adenosine triphosphate required in a eukaryotic cell and they contain their own genome. The mitochondrial DNA (mtDNA) is a double stranded circular molecule that codes for proteins required for cellular respiration and RNA molecules involved in translation of these proteins. READ MORE
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22. Carborane Derivatives for Nuclide Therapy and Imaging : Synthesis and Radio-labelling
Abstract : This thesis describes synthesis and radiohalogenation of closo-carborane and nido-carborate derivatives for application in nuclide therapy and imaging. The work could be divided in to four sections. READ MORE
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23. Conformationally Constrained Nucleosides, Nucleotides and Oligonucleotides : Design, Synthesis and Properties
Abstract : This thesis is based on six original research publications describing synthesis, structure and physicochemical and biochemical analysis of chemically modified oligonucleotides (ONs) in terms of their potential diagnostic and therapeutic applications. Synthesis of two types of bicyclic conformationally constrained nucleosides, North-East locked 1',2'-azetidine and North locked 2',4'-aza-ENA, is described. READ MORE
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24. Synthesis of DNA Intercalating Compounds for Nuclide Therapy
Abstract : .... READ MORE
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25. Polyamines are involved in the regulation of S phase and DNA synthesis
Abstract : Our research group has previously shown that treatment with the polyamine biosynthesis inhibitors a-difluoromethylornithine (DFMO) or amidinoindan-1-one 2´-amidinohydrazone (CGP 48664) inhibited S phase progression before any other cell cycle phase was affected. This study was undertaken to further investigate the role of polyamines in the regulation of S phase progression and DNA synthesis. READ MORE