Search for dissertations about: "DNA template"

Showing result 1 - 5 of 54 swedish dissertations containing the words DNA template.

  1. 1. Structure of eukaryotic DNA polymerase epsilon and lesion bypass capability

    University dissertation from Umeå : Medicinsk kemi och biofysik

    Author : Nasim Sabouri; Umeå universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA polymerase epsilon; DNA replication; Okazaki fragment; Translesion synthesis; DNA lesion; dNTP; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi;

    Abstract : To transfer the information in the genome from mother cell to daughter cell, the DNA replication must be carried out only once and with very high fidelity prior to every cell division. In yeast there are several different DNA polymerases involved in DNA replication and/or DNA repair. READ MORE

  2. 2. Role of yeast DNA polymerase epsilon during DNA replication

    University dissertation from Umeå : Medicinsk kemi och biofysik

    Author : Isabelle Isoz; Umeå universitet.; [2008]
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; DNA polymerase epsilon; eukaryotic DNA replication; fidelity; leading strand; Dpb2; VETERINARY MEDICINE Biochemistry and clinical chemistry; VETERINÄRMEDICIN Biokemi och klinisk kemi;

    Abstract : Each cell division, the nuclear DNA must be replicated efficiently and with high accuracy to avoid mutations which can have an effect on cell function. There are three replicative DNA polymerases essential for the synthesis of DNA during replication in eukaryotic cells. READ MORE

  3. 3. Sensitive Identification Tools in Forensic DNA Analysis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Hanna Edlund; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; forensic genetics; STRs; Y-chromosome; Pyrosequencing; mitochondrial DNA; skeletal remains; DNA extraction; MEDICINE; MEDICIN; Medicinsk genetik; Medical Genetics;

    Abstract : DNA as forensic evidence is valuable in criminal investigations. Implementation of new, sensitive and fast technologies is an important part of forensic genetic research. This thesis aims to evaluate new sensitive methods to apply in forensic DNA analysis including analysis of old skeletal remains. READ MORE

  4. 4. Bottom-up Fabrication of Functional DNA Nanostructures

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erik Lundberg; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; click chemistry; gel electrophoresis; self-assembly; cross-linking; lipid membrane; fixation; linear dichroism; nanotechnology; spectroscopy; fret; dna; triplex recognition;

    Abstract : This thesis demonstrates bottom-up fabrication of a fully addressable non-repetitive network on the nanometer scale, assembled by synthetic DNA molecules. Each side constitutes a unique sequence of 10 bases, i.e. 3. READ MORE

  5. 5. Functional and structural properties of eukaryotic DNA polymerase epsilon

    University dissertation from Umeå : Medicinsk biokemi och biofysik

    Author : Olga Chilkova; Umeå universitet.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; eukaryotic DNA replication; DNA polymerase epsilon; protein-DNA interaction; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi;

    Abstract : In eukaryotes there are three DNA polymerases which are essential for the replication of chromosomal DNA: DNA polymerase alpha (Pol alpha), DNA polymerase delta (Pol delta) and DNA polymerase epsilon (Pol epsilon). In vitro studies of viral DNA replication showed that Pol alpha and Pol delta are sufficient for DNA replication on both leading and lagging DNA strands, thus leaving the function of Pol epsilon unknown. READ MORE