Search for dissertations about: "DNA vaccine"

Showing result 6 - 10 of 121 swedish dissertations containing the words DNA vaccine.

  2. 6. Development of novel DNA vaccine and immunotherapeutic approaches

    Author : Maroof Hasan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Many potential DNA vaccination and immunotherapeutic strategies has been explored in both animal models and human settings in recent years. However, the failure of efficient and safe method development suggests that it is time to rethink, since more innovative approaches are needed for better control of infection and immunotherapy. READ MORE

  4. 7. Delivery of DNA vaccines against cancer

    Author : Anna-Karin Roos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : DNA vaccine; prostate-specific antigen; immunotherapy; prostate cancer; electroporation;

    Abstract : DNA vaccines against cancer have shown promising results in animal models. Efficient antigenspecific T cell responses and tumor protection have been demonstrated after vaccination with DNA encoding tumor antigens in mice. READ MORE

  5. 8. Implications of Local Puumala Hantavirus Genetics and Epidemiology for Diagnostics and Vaccine Development

    Author : Patrik Johansson; Fredrik Elgh; Göran Bucht; Detlev Krüger; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; hantavirus; Puumala virus; nephropathia epidemica; genome sequence; glycosylation; linear DNA vaccine; microarray; identification; genetic variability; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; medicinsk virologi; Medical Virology;

    Abstract : Puumala viruses, a member of the Hantavirus genus in the Bunyaviridae family, are enveloped by a lipid bilayer and possesses a tripartite single stranded RNA genome with negative polarity. The hantaviruses encode four proteins: a nucleocapsid protein (N), two membrane spanning glycoproteins (GN and GC) and a RNA dependent RNA polymerase (RdRp). READ MORE

  6. 9. Vaccine effectiveness against HPV infections

    Author : Hanna Kann; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Infections with human papilloma viruses (HPV) are the most prevalent sexually transmitted diseases. The vast majority of the sexually active population acquires them during lifetime but almost all HPV infections become resolved within a year. READ MORE

  7. 10. Enhancement of HIV-1 DNA immunogens

    Author : Anne Kjerrström Zuber; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HIV-1; DNA vaccination; regulatory genes; adjuvants; experimental HIV-1 model;

    Abstract : Human immunodeficiency virus type 1 eludes control by the immune response through a high degree of variability and immune escape mechanisms. Induction of a broad specific immune response is important to clear virus-infected cells. READ MORE