Search for dissertations about: "DNA vaccines"

Showing result 1 - 5 of 76 swedish dissertations containing the words DNA vaccines.

  1. 1. DNA vaccines and bacterial DNA in immunity

    University dissertation from Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Author : Lisa Charlotta Bandholtz; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA vaccine; CpG DNA; antimicrobial peptides C. pneumoniae; Shigella spp;

    Abstract : This thesis describes DNA-based vaccination and the importance of bacterial DNA in different immunological perspectives. Intranasal (i.n.) DNA vaccination utilizing a plasmid encoding the chlamydial heat shock protein 60 (p-hsp-60) generated lower bacterial burden and reduced pathology in the lungs of mice after subsequent infection with C. READ MORE

  2. 2. Rift Valley fever development of diagnostics and vaccines

    University dissertation from Umeå : Umeå university

    Author : Jonas Näslund; Umeå universitet.; Umeå universitet.; Umeå universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rift Valley Fever; vaccines; diagnostics; MEDICINE; MEDICIN; MEDICINE Microbiology; immunology; infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar; medicinsk virologi; Medical Virology; Infectious Diseases; infektionssjukdomar;

    Abstract : Rift Valley Fever virus (RVFV) causes an infection with severe impact on animal and human health. The disease is endemic throughout almost the entire African continent and large regions of the Arabian Peninsula. During epidemics, high mortality is observed in animals, especially among cattle, goats, and sheep. READ MORE

  3. 3. Delivery of DNA vaccines against cancer

    University dissertation from Stockholm : Karolinska Institutet, Department of Oncology-Pathology

    Author : Anna-Karin Roos; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA vaccine; prostate-specific antigen; immunotherapy; prostate cancer; electroporation;

    Abstract : DNA vaccines against cancer have shown promising results in animal models. Efficient antigenspecific T cell responses and tumor protection have been demonstrated after vaccination with DNA encoding tumor antigens in mice. READ MORE

  4. 4. Recombinant subunit vaccines : protein immunogens

    University dissertation from Institutionen för biokemi och biokemisk teknologi

    Author : Sissela Liljeqvist; KTH.; [1998]
    Keywords : ;

    Abstract : Recombinant techniques provide valuable tools for thedevelopment of modern subunit vaccines. In this thesisdifferent systems for production of recombinant subunitvaccines are presented. The strategies investigated includeprotein immunogens, live bacterial vectors and nucleicacids. READ MORE

  5. 5. Modulation of inflammation by immunostimulatory DNA

    University dissertation from Institutionen för biokemi och biokemisk teknologi

    Author : Jan Bjersing; Göteborgs universitet.; Gothenburg University.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CpG DNA; arthritis; phosphodiester; phosphorothioate; nucleotide modification; cytokines; chemokines; FcgammaR; B cell subsets.;

    Abstract : The aim of this thesis was to elucidate the roles of different types of DNA in inflammatory responses. We compared the immune responses to nuclease-protected phosphorothioate oligodeoxynucleotides (S-ODNs) and phosphodiester oligodeoxynucleotides (O-ODNs) that either contained or lacked CpG motifs. READ MORE