Search for dissertations about: "DNA vaccines"

Showing result 11 - 15 of 82 swedish dissertations containing the words DNA vaccines.

  2. 11. Enhancing T cell mediated immunity in DNA vaccination

    Author : Jan Alvar Lindencrona; Karolinska Institutet; Karolinska Institutet; []
    Keywords : DNA vaccination; CTL; T cell; IFN-gamma; anti-tumor immunity; HER-2 neu; Influenza; LCMV; Virus-Like Particles; murine models; adjuvants; immunotherapy;

    Abstract : For centuries infectious diseases have been one of the main causes of death in the world. With the invention of vaccine technology 200 years ago, we have been able to impede and even eradicate several dangerous pathogens. READ MORE

  4. 12. Development of novel DNA vaccine and immunotherapeutic approaches

    Author : Maroof Hasan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Many potential DNA vaccination and immunotherapeutic strategies has been explored in both animal models and human settings in recent years. However, the failure of efficient and safe method development suggests that it is time to rethink, since more innovative approaches are needed for better control of infection and immunotherapy. READ MORE

  5. 13. Induction of t-cell responses against PSA by plasmid DNA immunization

    Author : Maxim Pavlenko; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Prostate-specific antigen; DNA vaccine; cytotoxic T lymphocytes;

    Abstract : This thesis is focused on using plasmid DNA encoding human prostate-specific antigen (PSA) for immunotherapy of prostate cancer. PSA is a secreted serine protease, which is produced almost exclusively by prostate epithelial cells. READ MORE

  6. 14. In vivo bioluminescence imaging in preclinical trials of genetic vaccines

    Author : Stefan Petkov; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : DNA immunization is a rapidly developing vaccine platform for cancer, infectious disease, and allergies. The efficiency of DNA vaccination is largely determined by the efficiency of delivery and subsequent expression of the HIV-1 genes in the cells. READ MORE

  7. 15. In vivo bioluminescence imaging in preclinical trials of genetic vaccines

    Author : Stefan Petkov; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : DNA immunization is a rapidly developing vaccine platform for infectious diseases, cancer and allergies. The efficiency of DNA vaccination is largely determined by the efficiency of delivery and subsequent expression of genes encoding microbial and tumor antigens or allergens in the cells of vaccine recipients. READ MORE