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Found 3 swedish dissertations matching the above criteria.

  1. 1. The HDZip Class I Transcription Factors in Arabidopsis thaliana : Characterisation of HDZip Genes Involved in the Mediation of Environmental Signals

    Author : Eva Henriksson; Peter Engström; Julio Salinas; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plant physiology; Växtfysiologi; Plant physiology; Växtfysiologi;

    Abstract : Homeodomain leucine zipper (HDZip) proteins constitute a large family of transcription factors characterised by the presence of a DNA-binding homeodomain and an adjacent leucine zipper motif, which mediates protein-dimer formation. The HDZip genes of Arabidopsis have been divided into four classes, HDZip I-IV. READ MORE

  2. 2. Targeting of the Myc pathway as a novel approach for cancer therapy

    Author : Hao Mo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : oncogene; tumor suppressor gene; Myc; cellular screening; small molecules; MYRAs; NSC308848; camptothecin; paclitaxel; apoptosis; transcription; transformation.;

    Abstract : As transcription factors, Myc-family proteins function upstream of signaling pathways and regulate cell proliferation, differentiation, angiogenesis, apoptosis and transformation. Precisely regulated Myc expression is critical for cellular physiology, while perturbations of Myc expression have detrimental consequences to the organism. READ MORE

  3. 3. Structural insights into protein-protein interactions governing regulation in transcription initiation and ubiquitination

    Author : Madhanagopal Anandapadamanaban; Maria Sunnerhagen; Martin Moche; Marie Wahren-Herlenius; Cynthia Wolberger; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Virtually every aspect of the cellular processes in eukaryotes requires that the interactions between protein molecules are well coordinated in different regulatory pathways. Any protein dysfunction involved in these regulatory pathways might lead to various pathological conditions. READ MORE