Search for dissertations about: "DNA-repair"
Showing result 1 - 5 of 205 swedish dissertations containing the word DNA-repair.
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1. Bacterial DNA repair and molecular search
Abstract : Surveillance and repair of DNA damage is necessary in all kinds of life. Different types of DNA damage require different repair mechanisms, but these mechanisms are often similar in all domains of life. The most serious type of damage, double stranded DNA breaks, are for example repaired in conceptually similar ways in both bacteria and eukaryotes. READ MORE
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2. AtZDP, a Plant 3' DNA Phosphatase, Involved in DNA Repair
Abstract : DNA bases can be modified by endogenous agents (e.g. oxidized by products of respiration and photosynthesis or methylated by gene silencing processes) as well as by environmental agents (e.g. READ MORE
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3. DNA repair and the p53 pathway in ischemic and traumatic brain injury
Abstract : Ischemic and traumatic brain damage are major causes of disability and death. While much effort has been spent to develop pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. READ MORE
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4. Structural and dynamical basis of NusA´s role in transcription-coupled DNA repair
Abstract : DNA repair processes involves a host of repair machineries that are able to recognize and repair the damaged DNA. Nucleotide excision repair (NER) pathway is one of these processes exploited by cells to remove bulky DNA lesions. READ MORE
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5. Targeting DNA repair pathways for cancer therapy
Abstract : Accumulation of genomic mutations is the consequence of failure in DNA repair as well as increased exposure to endogenous/environmental mutagens. DNA repair pathways safeguard the human genome from such mutagens, and thereby suppress the multi-step process of carcinogenesis. READ MORE