Search for dissertations about: "DNAzyme"

Found 3 swedish dissertations containing the word DNAzyme.

  2. 1. Gene therapy tools: oligonucleotides and peptides

    Author : Jonas Eriksson; Ülo Langel; Jens Kurreck; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Gene therapy; oligonucleotide; peptide; RNA-cleaving deoxyribozyme; deoxyribozyme; DNAzyme; cell-penetrating peptide; CPP; enzyme; enzyme kinetics; kinetic assay; assay; telomerase; telomerase inhibitor; imetelstat; GRN163L; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Genetic mutations can cause a wide range of diseases, e.g. cancer. Gene therapy has the potential to alleviate or even cure these diseases. READ MORE

  4. 2. Biosensing platforms using graphene based bioreactive nanostructures with various dimensions

    Author : Yuanyuan Han; Klaus Leifer; Jöns Hilborn; Hu Li; Boukherroub Rabah; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Graphene; nanoparticles; nanostructure; biosensors;

    Abstract : Nanomaterials have brought new aspects and improvements to the biosensing field due to their unique physical and chemical properties that are not shown in the bulk state. This thesis focuses on concepting, developing and testing of biosensors where nanomaterials including graphene gold nanoparticles (AuNPs) and magnetic nanoparticles (MNPs) constitute the biosensors. READ MORE

  5. 3. Single-stranded DNA : methods and application in nanotechnology

    Author : Giulio Bernardinelli; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Basic molecular and cell research, production of recombinant proteins, diagnostic detection of genetic mutations, construction of nanostructures and high-throughput DNA sequencing are only a few examples of the diverse set of applications that are amenable thanks to the availability of synthetic DNA polymers in biomedicine. Strategic investments and technical progress together with the introduction of automation in the synthesis of DNA oligomers enabled to transform, in just a few decades, a process mastered only by a niche of biochemists into an affordable and available custom-made product to every scientific field. READ MORE