Search for dissertations about: "DOPA"
Showing result 1 - 5 of 93 swedish dissertations containing the word DOPA.
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1. Thiol-Ene CHemistry and Dopa-Functional Materials towards Biomedical Applications
Abstract : Thiol-ene chemistry is versatile and efficient and can be used as a powerful tool in polymer synthesis. In this thesis, the concept of thiol-ene chemistry has been central, where it has been explored as a tool for the synthesis of well-defined hydrogels and dopa-functional materials towards biomedical applications; such as hydrogels, primers for adhesive fixation of bone fractures, self-healing gels, and micelles for drug-delivery. READ MORE
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2. On dopamine neurons : nerve fiber outgrowth and L-DOPA effects
Abstract : Parkinson’s disease is a disorder mainly characterized by progressive degeneration of dopamine producing neurons in the substantia nigra of the midbrain. The most commonly used treatment strategy is to pharmacologically restore the lost function by the administration of the dopaminergic precursor L-DOPA. READ MORE
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3. Dysfunction in the nigrostriatal system : effects of L-DOPA and GDNF
Abstract : Parkinson’s disease is a common neurodegenerative disorder caused by nigrostriatal dopamine loss, with motor deficiencies as the primary outcome. To increase the striatal dopamine content, patients are treated with 3,4-dihydroxyphenyl-l-alanine (l-DOPA). READ MORE
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4. Involvement of non-dopaminergic systems in L-DOPA-induced dyskinsia
Abstract : Parkinson's disease and L-DOPA-induced dyskinesia (LID) does not merely involve the dopamine (DA) system but also include non-dopaminergic systems such as glutamate and serotonin (5-HT). An aberrant glutamate transmission at the corticostriatal synapse, has been linked to LID. READ MORE
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5. To metal, or not to metal : Diverse mechanisms of O2-activation and radical storage in the ferritin superfamily
Abstract : Proteins in the Ferritin-like superfamily are characterized by a four alpha-helical structural motif. These proteins are distributed across all three kingdoms of life and perform a wide range of functions. READ MORE