Search for dissertations about: "DPP-4 INHIBITORS"

Found 4 swedish dissertations containing the words DPP-4 INHIBITORS.

  2. 1. Novel insights into the regulation of insulin secretion by GLP-1, GIP and glucagon

    Author : Linda Ahlkvist; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vagus nerve; GPR119; Insulin resistance; Glucagon; GIP; GLP-1; Insulin;

    Abstract : There are many contributing factors to the development of type 2 diabetes, however, failure of beta-cells to sufficiently secrete insulin is the key component. The underlying mechanism of beta-cell failure is not fully established. In this thesis, we examined the role of high glucagon levels, i.e. READ MORE

  4. 2. Towards a Health Economic Simulation Model of Type 2 Diabetes in Sweden

    Author : Aliasghar Ahmad Kiadaliri; Hälsoekonomi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The aim of this thesis was to provide part of the data required in updating/developing computer simulation models (CSMs) for type 2 diabetes mellitus (T2DM) using data obtained from routine clinical practice in Sweden. In paper I, evolution of five biomarkers (i.e. READ MORE

  5. 3. Aspects of arterial wall healing : re-endothelialization, intimal hyperplasia and vascular remodeling

    Author : Samuel Röhl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular disease is the leading cause of mortality in the world. Despite prevention, the need for interventions remains high. Patients with type 2 diabetes mellitus have an increased cardiovascular burden and are at higher risk of complications following invasive vascular interventions. READ MORE

  6. 4. Save the brain! Studies on GLP-1-mediated neuroprotection

    Author : Martin Larsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Patients with type 2 diabetes (T2D) suffer stroke more often and have worse recovery. Moreover, hyperglycemic stroke patients treated with thrombolytic therapy have more intracranial bleedings. READ MORE