Search for dissertations about: "DPP-4 inhibition"
Found 4 swedish dissertations containing the words DPP-4 inhibition.
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1. On Meal Effects and DPP-4 Inhibition Islet- and Incretin Hormones in Health and Type 2 Diabetes
Abstract : .... READ MORE
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2. Glucagon Counter-Regulation to Hypoglycemia During Incretin-Based Therapy
Abstract : Incretin-based therapy is associated with low risk of hypoglycemia in type 2 diabetes mellitus (T2DM) possibly due to its glucose-dependency in stimulating insulin secretion and a sustained glucagon response during hypoglycemia. This is of special relevance when it is combined with insulin or given to elderly patients since both insulin therapy and high age are associated with impaired glucagon counter-regulation. READ MORE
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3. Novel insights into the regulation of insulin secretion by GLP-1, GIP and glucagon
Abstract : There are many contributing factors to the development of type 2 diabetes, however, failure of beta-cells to sufficiently secrete insulin is the key component. The underlying mechanism of beta-cell failure is not fully established. In this thesis, we examined the role of high glucagon levels, i.e. READ MORE
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4. Aspects of arterial wall healing : re-endothelialization, intimal hyperplasia and vascular remodeling
Abstract : Cardiovascular disease is the leading cause of mortality in the world. Despite prevention, the need for interventions remains high. Patients with type 2 diabetes mellitus have an increased cardiovascular burden and are at higher risk of complications following invasive vascular interventions. READ MORE