Search for dissertations about: "DRB1"

Showing result 6 - 10 of 88 swedish dissertations containing the word DRB1.

  2. 6. HLA genetics in multiple sclerosis

    Author : Jenny Link; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic disease in which both genetic and environmental risk factors contribute to disease susceptibility. MS patients suffer from inflammatory lesions in the central nervous system which results in demyelination of nerve cells, reduced neuronal activity and finally neurodegeneration. READ MORE

  4. 7. Studies of different clinical manifestations of Sarcoidosis and the role of genetic factors

    Author : Pernilla Darlington; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Sarcoidosis is a systemic disease of unknown etiology characterized by the formation of non-necrotizing granulomas in the affected organs. Engagement of the lungs and/or thoracic lymph nodes (LN) are found in more than 90 % of all cases, but almost any organ such as the eyes, skin, heart and nervous system can be involved. READ MORE

  5. 8. HLA, salivary IgA and mutans streptococci - is there a relation?

    Author : Marie Louise Wallengren; Malmö högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunoglobulin A; Streptococcus mutans; Streptokocker; Karies;

    Abstract : Mutansstreptokocker (MS) är en grupp bakterier som i många studier visats ha ett starkt samband med karies. Bakterierna anses tillhöra vår normala munflora, men alla individer har inte MS och mängden skiljer sig mycket från en individ till en annan. Orsakerna till denna variation är till viss del välkända, som t.ex. READ MORE

  6. 9. Genetic Risk Factors for Cervical Carcinoma in situ

    Author : Anna Beskow; Peter L Stern; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Cervical carcinoma; human papillomavirus; viral load; long-term infection; HLA class II; p53; E6 variant; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Abstract : Oncogenic human papillomaviruses (HPVs) are implicated in 99.7 % of cervical cancer cases but require the co-operation of other factors. To investigate potential genetic risk factors we have typed the HLA class II DRB1 and DQB1 loci in 478 women diagnosed with cervical carcinoma in situ and in 608 age-matched controls. READ MORE

  7. 10. Studies of risk loci in multiple sclerosis

    Author : Magdalena Lindén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system, is one of the most common causes of neurological disability among young adults. While the etiology is unknown, an increasing number of environmental and genetic risk factors is being identified. READ MORE