Search for dissertations about: "DRD4"

Found 4 swedish dissertations containing the word DRD4.

2. 1. Genes that modulate or mediate dopaminergic neurotransmission : expression of the human prodynorphin gene and association studies with candidate genes in an alcohol patient sample

   Author : Thomas Geijer; Karolinska Institutet; Karolinska Institutet; []
   Keywords : association study; alcoholism; DNA polymorphisms; dopamine receptors DRD2; DRD3; DRD4 ; tyrosine hydroxylase TH ; prodynorphin; messengerRNA; gene expression; promotor Stockholm 1997;

   Abstract : The development of alcoholism may at least partly be attributed to the effect of ethanol on reward and reinforcement. As a genetic influence in the vulnerability to alcoholism and drug abuse has been documented, it is of interest to investigate genes active in brain structures which mediate reward and reinforcement. READ MORE

4. 2. Genetic aspects on schizophrenia and cerebrospinal fluid monoamine metabolites : focus on association studies with candidate genes

   Author : Erik Jönsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : association study; schizophrenia; DNA polymorphisms; dopamine receptors DRD2; DRD3; DRD4 ; tyrosine hydroxylase; tryptophan hydroxylase; catechol-O-methyltransferase; neurotrophin-3; ciliary neurotrophic factor; healthy subjects; cerebrospinal fluid;

   Abstract : Schizophrenia is a syndrome with psychotic symptoms. The pathogenesis of schizophrenia most likely reflects brain abnormalities and heritable components are present. The principal objective of the present thesis was to investigate some possible genetic influences in the genesis or pathophysiology of schizophrenia. READ MORE

5. 3. Suicide attempt and genes : psychiatric and genetic characteristics of suicide attempters

   Author : Maj-Liz Persson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Suicide; Attempted; Mental disorders; Association; Genetic markers; Serotonin; Norepinephrine; Dopamine;

   Abstract : Suicide affects an appreciable number of people in all societies. Finding genes that predispose to suicidal behavior may help to identify individuals at risk and an appropriate counseling and support can be extended to them. The studies of the present thesis focus on suicide attempt. READ MORE

6. 4. Stability and validity of self-reported personality traits

   Author : Petter J Gustavsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Karolinska Scales of Personality KSP ; personality traits; stability; outcome behavioral genetics; biological and clinical correlates Stockholm 1997;

   Abstract : Background: People differ, and these differences are often attributed to individual differences in certain personality traits assumed to have 'more than nominal value' and to 'exist within' the individual. The aim of the present study was to evaluate some properties of a trait assessment instrument, the Karolinska Scales of Personality (KSP). READ MORE