Search for dissertations about: "DRG"

Showing result 11 - 15 of 71 swedish dissertations containing the word DRG.

  2. 11. The effects of neurotrophic substances on primary sensory neurons following peripheral nerve injury

    Author : Petri Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : DRG; dorsal horn; NGF; BDNF; NT-3; substance P; calcitonin gene-related peptide; fluoride-resistant acid phosphatase; carbonic anhydrase; microglia; astroglia;

    Abstract : Sensory impulses from the periphery is transmitted by primary sensory neurons located in dorsal root and cranial nerve ganglia. The primary sensory neurons are phenotypically diverse with regard to their expression of various chemical components. READ MORE

  4. 12. Histochemical, biochemical and electrophysiological studies on dorsal root ganglion cultures : focusing on galanin, neuropeptide Y and glutamate

    Author : Nora Kerekes; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Acute and long-term DRG cultures; aFGF; BDNF; bFGF; bradykinin; excitability; galanin; glutamate; leukemia inhibitory factor; neuropeptide Y; : NGF; regeneration; whole cell patch clamp.;

    Abstract : Galanin (Gal) and neuropeptide Y (NPY) are two peptides, which are strongly up- regulated in a population of dorsal root ganglion (DRG) neurons after peripheral nerve injury (axotomy). Both peptides may be involved in the control of pain sensation, especially after nerve injury (neuropathic pain). READ MORE

  5. 13. On traumatic lesion to the spinal cord and dorsal spinal roots : factors influencing axonal regrowth across the border between the central and peripheral nervous system in the rat and man

    Author : Tomas Lindholm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Immunohistochemistry; in situ hybridization; rat; man; axotomy; regeneration; motoneuron; ; CNS; PNS; tenascin; macrophages; BBB; scar; neuregulin; ErbB3 4; semaphorin; neuropilin; VEGF; olfactory system; DRG; DRT; SNT; SNC.;

    Abstract : Nerve cells are depending on their environment. Glial cells, astrocytes and oligodendrocytes in the central nervous system (CNS) make up a totally different milieu and characteristics than the distinguishing qualities of the peripheral nervous system (PNS), where the nerve cells are surrounded by Schwann cells. READ MORE

  6. 14. Role of calcitonin gene-related peptide in nociception : interactions with substance P and opioids

    Author : Long-Chuan Yu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Calcitonin gene-related peptide CGRP ; CGRP8-37; CGRP-like immunoreactivity; carrageenan; dorsal horn; dorsal root ganglion DRG ; experimentally-induced inflammtion ß-funaltrexamine ß-FNA ; hindpaw withdrawl latency HWL ; hot-plate test; ;

    Abstract : This thesis presents a study of calcitonin gene-related peptide (CGRP) and its antagonist CGRP8-37 and the interactions with substance P and opioids on the transmission of presumed nociceptive information at the spinal cord level in the rat. Significant bilateral increases in hindpaw withdrawal latency (HWL) to heat and mechanical stimulation were induced dose-dependently by intrathecal administration of 5 or 10 but no 1 nmol of CGRP8-37. READ MORE

  7. 15. Navigating in the Midst of Uncertainties : Challenges in Disaster Risk Governance in Mozambique

    Author : Jenni Koivisto; Lars Nyberg; Mikael Granberg; Daniel Nohrstedt; Per Becker; Karlstads universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; disaster risk governance; Mozambique; disaster risk reduction; Risk and Environmental Studies; Risk- och Miljöstudier;

    Abstract : Disasters cause heavy losses for societies and may quickly erode any development efforts. Consequently, disaster risk reduction (DRR) is an integral part of development work that should be addressed at multiple levels. READ MORE