Search for dissertations about: "DRG"
Showing result 21 - 25 of 71 swedish dissertations containing the word DRG.
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21. Expression of stimulatory and inhibitory molecules in interactions between natural killer cells neurons
Abstract : Natural killer (NK) cells are important effector cells of the innate and the early induced immune defense. In the nervous system they appear early during inflammation and have been ascribed a role in clearance of certain viral infections from the brain. NK cells are regulated by multiple signals transmitted via inhibitory and stimulatory receptors. READ MORE
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22. Effects of intervertebral disc cells on neural tissue. In vitro and in vivo experimental studies
Abstract : Introduction: Lumbar disc herniation and sciatica are common conditions that involve interactions between intervertebral discs (IVDs) and neural tissue. The nucleus pulposus (NP) of an IVD contains at least two cell populations, notochordal cells and chondrocyte-like cells. READ MORE
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23. Neuronal tracers for fine caliber spinal primary afferents and their response to peripheral nerve injury
Abstract : The isolectin B4 from Griffonia simplicifolia I (B4) and soybean agglutinin from the plant Glycine max (SBA), have been shown to bind to rat small-diameter dorsal root ganglion (DRG) neurons, and to fibers and presumed terminals in laminae I-II of the spinal cord dorsal horn. In the present thesis, these lectins and/or their horseradish peroxidase (HRP) conjugates, have been investigated in the rat with regard to their usefulness as selective neuronal markers of and axonally transported tracers for somatic and/or visceral spinal primary afferents with fine caliber, including unmyelinated, axons. READ MORE
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24. Tetrodotoxin-resistant sodium channels in neuropathic pain
Abstract : Injury to the peripheral nervous system can cause neuropathic pain. Abnormal sodium channel activity has been implicated as a source of ectopic firing and changes in nociceptive threshold following nerve injury. READ MORE
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25. Investigating a cell replacement therapy in the inner ear
Abstract : The mammalian auditory system is sensitive to genetic disorders, aging and injuries caused by overstimulation, ototoxic drugs and viral infections. Since the sensory epithelium (the organ of Corti) and the spiral ganglion neurons (SGNs) in adult mammalian do not regenerate spontaneously when they are damaged, a cell substitution strategy was proposed to compensate the function of the degenerated SGNs. READ MORE