Search for dissertations about: "DRG"

Showing result 6 - 10 of 71 swedish dissertations containing the word DRG.

2. 6. Anti-Apoptotic Proteins in Nerve Cell Survival and Neurodegeneration

   Author : Laura Korhonen; Marja Jäättelä; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; neuronal cell death; XIAP; RIAP-2; Hippocalcin; Bcl-2; Bcl-X; kainic acid; DRG; estrogen; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

   Abstract : Apoptosis is a genetically regulated cell death program, which shows distinct morphological characteristics. It takes place during neuronal development and in some neurodegenerative diseases. During apoptosis, the intracellular proteins are degraded by various caspases, cysteine aspartases, which are regulated by pro- and anti-apoptotic signals. READ MORE

4. 7. Studies on Peripheral Nerve Regeneration: Microdispensing, Neurite Guidance and Galectins

   Author : Per Gustavsson; Funktionell zoologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; vävnadskultur; histokemi; cytokemi; Histologi; tissue culture; histochemistry; cytochemistry; Histology; Schwann cells; sciatic nerve; dorsal root ganglia; DRG; neurite guidance; galectins; inkjet; microdispensing; peripheral nervous system; nerve regeneration; Animal physiology; Djurfysiologi; Biotechnology; Bioteknik;

   Abstract : The present thesis describes development of a microdispenser-based technique to create of protein patterns for neurite guidance. The same technique was also developed to allow direct positioning of dissociated cells, including neurons, on cell culture substrates. Finally the role of galectin-3 and 8 during nerve regeneration was investigated. READ MORE

5. 8. Cell activation and nerve regeneration following peripheral nerve injury

   Author : Annika Widerberg; Malmö Handkirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; nerve regeneration; Nerve injury; conditioning lesion; nerve graft; tourniquet compression; vibration; DRG; Schwann cell; p75; CPON; neurofysiologi; neuropsykologi; Neurologi; neurophysiology; neuropsychology;

   Abstract : The effect of short time vibration exposure and tourniquet compression on nerve regeneration in rats was studied with special reference to cell activation. One of the hindlimbs was conditioned by either vibration exposure (5 hours / day - 5 consecutive days) or compression (150-300 mmHg for 30-120 minutes), which was followed by a recovery period of 0-7 days. READ MORE

6. 9. Bioelectronic Devices for Targeted Drug Delivery and Monitoring of Microbial Electrogenesis

   Author : Arghyamalya Roy; Daniel T Simon; Klas Tybrandt; Christopher Proctor; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Electrophoresis; Extracellular Electron Transfer EET ; Ion Exchange Membranes IEM ; Drug Delivery; Bupivacaine; Chronic Neuropathic Pain; Microfabrication; Inkjet Printing; Organic Electrochemical Transistor OECT ; Fumarate; Shewanella oneidensis; Dorsal Root Ganglia DRG ; Organic Electronic Ion Pump OEIP ;

   Abstract : Despite a range of pain therapies available in the market, 70% of patients report so-called “breakthrough pain”. Coupled with global issues like opioid crisis, there is a clear need for advanced therapies and technologies for pain management. READ MORE

7. 10. Prion processing and propagation in neuronal and dendritic cell culture models

   Author : Katarina M Luhr; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Prion; scrapie; cathepsin; processing; IFN-gamma; DRG; dendritic cell; cytokine;

   Abstract : Prion diseases are rare neurodegenerative diseases, associated with a conversion of a normal cellular protein, PrPC, into its misfolded and partial protease resistant isoform, PrPSc. These diseases affect both animals and humans and are unique since they can not only be genetic and sporadic, but also transmissible. READ MORE