Search for dissertations about: "DSC"

Showing result 11 - 15 of 151 swedish dissertations containing the word DSC.

  2. 11. Insight into the mitochondrial apoptotic pathway : The interplay of the pro-apoptotic Bax protein with oxidized phospholipids and its counterplayer, the pro-survival Bcl-2 protein

    Author : Marcus Wallgren; Gerhard Gröbner; Marco Colombini; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; apoptosis; Bax; Bcl-2; CD; cell-free protein synthesis; DSC; membrane; mitochondria; oxidized phospholipids; reconstitution; solid state NMR; biologisk kemi; biological chemistry;

    Abstract : Apoptosis plays a crucial role in multicellular organisms by preserving tissue homeostasis and removing harmful cells. The anti-apoptotic B-cell CLL/lymphoma 2 (Bcl-2) and the pro-apoptotic Bcl-2-associated X protein (Bax) act as major regulators of the mitochondrial apoptotic pathway. READ MORE

  4. 12. Effect of hydration on thermodynamic, rheological and structural properties of mucin

    Author : Yana Znamenskaya; Malmö högskola; []
    Keywords : mucous gel; mucus; mucin; PGM; BSM; BSM chitosan multilayers; hydration; water sorption isotherm; relative humidity; water activity; bound water; enthalpy of hydration of biopolymer; glass transition; rheology; phase diagram; fiber-like structure; dumbbell-like structure; sorption calorimetry; DSC; QCM-D; SAXS; AFM;

    Abstract : Mucus, an adherent hydrated layer covering the epithelium, is found in all internal tracts of the body and plays an important role in animal and human life. One of the essential functions of mucus is protection of tissues against dehydration. READ MORE

  5. 13. The Role of Sugars for Protein Stabilization

    Author : Christoffer Olsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; protein; water; QENS; biomolecule; EPSR; amorphous; trehalose; neutron scattering; cryopreservation; DSC; neutron diffraction; dielectric spectroscopy;

    Abstract : The understanding of biomolecular interactions with water and co-solutes can lead to greater knowledge regarding the mechanisms behind biomolecular stabilization. This is highly important for developing technologies aimed to preserve biological materials. READ MORE

  6. 14. Interactions of Anticancer Active Platinum(II) Complexes with DNA

    Author : Johan Kjellström; Bröstcancer-genetik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Inorganic chemistry; polyelectrolyte; medium effects; salt dependence; DSC; CD; HPLC; oligonucleotide; hairpin; DNA; anticancer active platinum II compounds; kinetics; mechanism; Oorganisk kemi; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : The kinetics and mechanism for interactions of the anticancer active platinum(II) complexes cis-[PtCl2(NH3)2)], cis-[PtCl2(NH3)(c-C6H11NH2)], and trans-[PtCl2-(NH3)(quinoline)] with DNA have been studied using a combination of HPLC, circular dichroism (CD), UV/vis spectroscopy, and differential scanning calorimetry (DSC). Reactions of the monoaqua forms (charge = +1) of these complexes with single-stranded DNA oligonucleotides, typically between 13-17 bases long, were found to depend on i) the composition of the reaction medium, ii) the exact nature and location of the platination target, and iii) on the DNA structure. READ MORE

  7. 15. RNA in model lipid membranes - interactions in bulk and at surfaces

    Author : Agnes Michanek; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ssRNA; RNA origami; dsDNA; selfassembly phospholipids; model membranes; monolayer; QCM-D; DSC; Neutron reflectometry; hydrophobic interaction; cationic surfactants; sphingosine; phase behavior;

    Abstract : The work presented in the thesis “RNA in model lipid membranes- interactions in bulk and at surfaces” aims to characterize the interaction between RNA and model membranes with different properties as well as to determine if ssRNA associate with model membranes in different ways. Several techniques have been used to characterize these systems, including quartz crystal microbalance with dissipation monitoring (QCM-D), Langmuir film balance in combination with neutron reflectometry and fluorescence microscopy as well as differential scanning calorimetry (DSC) and isothermal titration calorimetry (ITC). READ MORE