Search for dissertations about: "DTH"

Showing result 6 - 10 of 10 swedish dissertations containing the word DTH.

  2. 6. Dendritic cell presentation of type II collagen

    Author : Meirav Holmdahl; Lund Dermatologi och venereologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; chromosome 2; arthritis; proteases; antigen presentation; Dendritic cell; type II collagen;

    Abstract : Type II collagen (CII) is the main protein component of cartilage and immune recognition of CII plays a critical role for the development of collagen induced arthritis (CIA), a widely used animal model for rheumatoid arthritis (RA). Antigen presentation is an important requirement for the immune response, the more efficient presentation of the antigen the better tolerance will be induced and thereby protect against arthritis. READ MORE

  4. 7. Genetic Factors and Nasal Tolerance in Rat Models for Rheumatoid Arthritis

    Author : Shemin Lu; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nasal tolerance; linkage analysis; MHC; genetics; pristane induced arthritis; rheumatoid arthritis; collagen induced arthritis; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : We used three animal models of rats for rheumatoid arthritis (RA) in this study. Firstly, We found that CXI induced arthritis (CXIIA) is associated with the RT1 f haplotype and follows a chronic disease course affecting peripheral joints with both progression and relapses. READ MORE

  5. 8. Studies in DNA immunization

    Author : Cecilia Svanholm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chlamydia pneumoniae; DNA vaccine; GM-CSF; HIV-1; hsp60; Nef; Rev; Tat; signal sequence;

    Abstract : This thesis describes investigations and developments of DNA immunization techniques, which were applied in the study of two different pathogens; HIV-1 and Chlamydia pneumoniae. DNA vaccines, i.e. naked plasmid DNA encoding an antigen, represent a novel strategy for generating protective immunity against several infectious diseases. READ MORE

  6. 9. Genetic modification of cholera toxin B subunit for mucosal anti-infectious or anti-pathologic vaccination

    Author : Hamid Sadeghi; Göteborgs universitet; []
    Keywords : Genetic fusion protein; cholera toxin B subunit; insulin; GST; Oral tolerance;

    Abstract : The development of mucosal vaccines requires antigen delivery systems that can efficiently help to present vaccine antigens to the mucosal immune system. En efficient and well known antigen carrier/delivery system is the B subunit of cholera toxin (CTB). READ MORE

  7. 10. Effects of intestinal worms on skin immunity and control of co-infection

    Author : Cajsa Classon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Intestinal helminth infections remain a major health concern in developing areas of the world. Consequences of infection range from gastrointestinal discomfort to systemic manifestations. It has been suggested that individuals infected with intestinal helminths are more susceptible to other infections and mount weaker immunity to vaccination. READ MORE