Search for dissertations about: "Dan I. Andersson"

Showing result 1 - 5 of 28 swedish dissertations containing the words Dan I. Andersson.

  2. 1. Multi-omics investigation into bacterial evolution

    Author : Karl Dyrhage; Siv Andersson; Dan I. Andersson; Jay Hinton; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; bacterial evolution; cellular complexity; comparative genomics; transcriptomics; proteomics; fructophilic lactic acid bacteria; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Abstract : The focus of this thesis is the investigation of the evolution and cellular processes of Tuwongella immobilis and Apilactobacillus kunkeei, two bacterial species with different levels of genomic and cellular complexity, using a multi-omics approach.In the first study we examined the proteome of T. READ MORE

  4. 2. From Penicillin Binding Proteins to Community Interventions : Mathematical and Statistical Models Related to Antibiotic Resistance

    Author : Patricia Geli Rolfhamre; Åke Svensson; Mikael Andersson; Dan I. Andersson; Karl Ekdahl; Bruce R. Levin; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistance; mathematical modeling; pharmacokinetics; pharmacodynamics; penicillin binding protein; postantibiotic effect; reversibility; selection; community intervention; Mathematical statistics; Matematisk statistik; matematisk statistik; Mathematical Statistics;

    Abstract : Antibiotic resistance has become a major public health concern and mathematical models are important analytical tools for the understanding, evaluation and prediction of the resistance problem and related control strategies.The risk of emerging antibiotic resistance and selection has rarely been a concern in the design of antibiotic drug dosing regimens. READ MORE

  5. 3. Translational accuracy and bacterial growth

    Author : Dan I. Andersson; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  6. 4. Removal and Replacement of Ribosomal Proteins : Effects on Bacterial Fitness and Ribosome Function

    Author : Christina Tobin; Dan I. Andersson; Richard Buckingham; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; ribosome; protein synthesis; ribosomal proteins; translation initiation; ribosome biogenesis; fitness costs; compensatory evolution; horizontal gene transfer; Microbiology; Mikrobiologi; Biochemistry; Biokemi; Mikrobiologi; Microbiology;

    Abstract : Protein synthesis is a complex process performed by sophisticated cellular particles known as ribosomes. Although RNA constitutes the major structural and functional component, ribosomes from all kingdoms contain an extensive array of proteins with largely undefined functional roles. READ MORE

  7. 5. Mechanisms and Dynamics of Mecillinam Resistance in Escherichia coli

    Author : Elisabeth Thulin; Dan I Andersson; Laura Piddock; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mecillinam; Antibiotic resistance; Escherichia coli; Urinary tract infections; Fitness; Penicillin binding proteins; cysteine biosynthesis; Mikrobiologi; Microbiology;

    Abstract : The introduction of antibiotics in healthcare is one of the most important medical achievements with regard to reducing human morbidity and mortality. However, bacterial pathogens have acquired antibiotic resistance at an increasing rate, and due to a high prevalence of resistance to some antibiotics they can no longer be used therapeutically. READ MORE