Search for dissertations about: "Daniel V. Oliveira"

Found 1 swedish dissertation containing the words Daniel V. Oliveira.

2. 1. Unraveling the role of NOTCH3 dysfunction in disease and for therapy development : a focus on CADASIL

   Author : Daniel V Oliveira; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The Notch signaling pathway, including the Notch3 receptor, is involved in many pivotal contexts of cell signaling and cell fate determination processes during development and in adulthood. Different mutations in the NOTCH3 receptor, which is highly expressed in vascular smooth muscle cells (VSMC), are associated with various diseases, including developmental disorders, several forms of cancer, and vascular dementia. READ MORE