Search for dissertations about: "David Josephy"

Found 1 swedish dissertation containing the words David Josephy.

2. 1. Design of Glutathione Transferase Variants for Novel Activities with Alternative Substrates

   Author : Abeer Shokeer; Bengt Mannervik; Francoise Raffalli-Mathieu; David Josephy; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Organic chemistry; Organisk kemi; Biokemi; Biochemistry; Organisk kemi; Organic Chemistry;

   Abstract : Glutathione transferases (GSTs) play a pivotal role in cellular defense, since they are main contributors to the inactivation of genotoxic compounds of exogenous and endogenous origins. Directed evolution was used to improve the catalytic activities of Theta class GST T1-1 toward different substrates. READ MORE