Search for dissertations about: "Dennis A Smith"

Found 2 swedish dissertations containing the words Dennis A Smith.

  1. 1. In vivo Pharmacokinetic Interactions of Finasteride and Identification of Novel Metabolites

    Author : Anna Lundahl; Hans Lennernäs; Dennis A Smith; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; drug-drug interactions; herb-drug interactions; pharmacokinetics; metabolism; CYP3A4; hydroxylation; glucuronidation; UGT enzymes; mass spectrometry; biliary excretion; urinary excretion; finasteride; PHARMACY; FARMACI;

    Abstract : The general aim of this thesis was to improve the understanding of the in vivo pharmacokinetics and, in particular, the metabolism of finasteride, a 5α-reductase inhibitor used in the treatment of enlarged prostate glands and male pattern baldness. CYP3A4 has been identified as the major enzyme involved in the sequential metabolism of finasteride to ω-OH finasteride (M1) and ω-COOH finasteride (M3). READ MORE

  2. 2. Wireless Multi-Sensor Feedback Systems for SportsPerformance Monitoring : Design and Development

    Author : Dennis Sturm; Lars-Åke Brodin; Kjartan Halvorsen; Martin Eriksson; Kaj Lindecrantz; Richard Smith; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; kayak; paddle; mobile phone; sports performance; propulsive force; boat velocity; sampling frequency; wireless measurement; wireless sensor; Kayak XL System; sensor piconet; sensor platform; user-centred design;

    Abstract : Wireless applications have become a common part of daily life. Whether it is mobile phones, the Wi-Fi router at home, the keycard which has replaced the car key, a radio frequency identification access system to a building or a Bluetooth headset for your computer or phone, the means of modern wireless data exchange is an omnipresent technology. READ MORE