Search for dissertations about: "Desorption Electrospray Ionization"

Showing result 1 - 5 of 25 swedish dissertations containing the words Desorption Electrospray Ionization.

  1. 1. Applications of nanospray desorption electrospray ionization mass spectrometry : In situ lipid and metabolite analysis from cells to tissue

    Author : Hilde-Marléne Bergman; Ingela Lanekoff; Jonas Bergquist; Martina Marchetti-Deschmann; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; Mass spectrometry; mass spectrometry imaging MSI ; nanospray desorption electrospray ionization nano-DESI ; single-cell analysis; neurotransmitter imaging; diabetic nephropathy; pneumatic nebulization; lipidomics; metabolomics; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Abstract : Ambient mass spectrometry (MS) has proved to be an important addition to the bioanalytical toolbox. These methods perform analyte sampling and ionization under atmospheric pressure, and require very little sample preparation other than the sampling process in front of the machine. READ MORE

  2. 2. Applications of nanospray desorption electrospray ionization mass spectrome : Analysis of lipids and metabolites in brain tissue sections and single cells

    Author : Hilde-Marléne Bergman; Ingela Lanekoff; Jonas Bergquist; Leopold Ilag; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Nano-DESI; single cell analysis; small molecule neurotransmitters; mass spectrometry imaging; MSI; GABA; Glutamate; Acetylcholine; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Abstract : .... READ MORE

  3. 3. Electrophoretic focusing in microchannels combined with mass spectrometry : Applications on amyloid beta peptides

    Author : Saara Mikkonen; Åsa Emmer; Johan Jacksén; Tapio Kotiaho; KTH; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; amyloid beta; computer simulation; electrophoresis; electrospray ionization; isoelectric focusing; isotachophoresis; MALDI; mass spectrometry; microchannel; microchip; nano-electrospray ionization; preconcentration; separation; Kemi; Chemistry;

    Abstract : Analysis of low-abundance components in small samples remains a challenge within bioanalytical chemistry, and new techniques for sample pretreatments followed by sensitive and informative detection are required. In this thesis, procedures for preconcentration and separation of proteins and peptides in open microchannels fabricated on silicon microchips are presented. READ MORE

  4. 4. New Materials and Improved Ambient Techniques in Mass Spectrometry

    Author : Nicolò Riboni; Leopold Ilag; Elisa Robotti; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Solid Phase Microextraction; Ambient Mass Spectrometry; Desorption Electrospray Ionization; Paper Spray Ionization; Cavitands; BTEX; New Psychoactive Substances; Analytical Chemistry; analytisk kemi;

    Abstract : Mass spectrometry (MS) is used in several fields, e.g. biology, environmental monitoring, medicine and forensics due to excellent qualitative and quantitative capabilities. The development of new instrumental setups and ionization sources is crucial to analyze a variety of compounds at trace levels. READ MORE

  5. 5. Sample preconcentration in open microchannels : Combinations with MALDI and nano-ESI mass spectrometry and computer simulations

    Author : Saara Mikkonen; Åsa Emmer; Leopold Ilag; Jenny Ottosson Takanen; KTH; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Preconcentration; open microchannel; microchip; MALDI; electrospray ionization; nanoelectrospray; mass spectrometry; computer simulation;

    Abstract : In this thesis a novel concept for preconcentration of biomolecules in open microchannels is presented. The preconcentration is based on electromigration of charged analytes, and detection is performed with matrix-assisted laser desorption/ionization (MALDI) or nano-electrospray ionization (nESI) mass spectrometry (MS). READ MORE