Search for dissertations about: "Desorption Electrospray Ionization"
Showing result 21 - 25 of 27 swedish dissertations containing the words Desorption Electrospray Ionization.
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21. Mass spectrometry in peptide and tumor marker analysis
Abstract : Integration of preparative protein and peptide separations with analytical techniques, in particular mass spectrometry (MS), is important. This thesis describes preparation via capillary electrophoresis and two-dimensional (2-D) gel electrophoresis for identification and structure determination of polypeptides. READ MORE
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22. Development of Methods for Protein and Peptide Analysis Applied in Neuroscience Utilizing Mass Spectrometry
Abstract : This thesis describes the utilization of the matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) and electrospray ionization (ESI) MS techniques for analysis of complex brain tissue samples. Direct molecular profiling of biological samples using MALDI MS is a powerful tool for identifying phenotypic markers. READ MORE
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23. Analytical developments and applications of ambient mass spectrometry imaging : Visualizing challenging analytes and understanding chemical mechanisms of ischemic stroke
Abstract : Bioanalytical methods that provide spatial information on molecular distributions are important for deep understanding of chemical mechanisms in health and disease. For instance, the localized action of drugs and metabolites can provide valuable information on metabolism in specific cellular regions, which would not be possible with bulk analysis. READ MORE
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24. Lipoproteomics : mapping of proteins in LDL and HDL
Abstract : High-density lipoprotein (HDL) and (LDL)-density lipoprotein (LDL) are important lipoprotein fractions in human plasma. HDL is the most abundant lipoprotein particle and a negative risk factor of atherosclerosis while LDL is considered to possess atherogenic properties. READ MORE
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25. Lipoproteomics : A New Approach to the Identification and Characterization of Proteins in LDL and HDL
Abstract : A proteomic approach was applied to examine the protein composition of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) in humans. LDL and HDL were isolated by density gradient ultracentrifugation, and proteins were separated with twodimensional gel electrophoresis (2-DE) and identified with peptide mass fingerprinting, using matrix-assisted laser desorption/ionization-time of flight mass spectrometry, and with amino acid sequencing using electrospray ionization tandem mass spectrometry. READ MORE