Search for dissertations about: "Det beror på:"

Showing result 21 - 25 of 1001 swedish dissertations containing the words Det beror på:.

  2. 21. SOX11 as a Cancer Biomarker - Expression and Regulatory Studies in B-cell Lymphomas and Ovarian Cancer

    Author : Elin Gustavsson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SOX11; B-cell lymphomas; DNA methylation; cancer biomarkers; ovarian cancer;

    Abstract : It is estimated that one third of all people in Sweden will be diagnosed with cancer during their lifetime. The outcome for a specific patient is related to early and correct diagnosis, and prediction of effective treatment regimens. Biomarkers are molecules that can aid the clinician in such decisions regarding diagnosis, prognosis and therapy. READ MORE

  4. 22. Interactions of human C4BP with Bordetella pertussis and Streptococcus pyogenes

    Author : Karin Berggård; Lund Dermatologi och venereologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; M protein; antigenic variation; phagocytosis resistance; complement; C4b-binding protein C4BP ; Bordetella pertussis; Streptococcus pyogenes; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Many microorganisms have developed mechanisms to protect themselves against attack from the complement system of the host. One possible mechanism for a microorganism to evade complement attack is to bind a human complement regulator, which may allow the microorganism to down-regulate complement activation. READ MORE

  5. 23. Building a map of the breast cancer proteome - Strategies to increase coverage

    Author : Paolo Cifani; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Quantitative proteomics; Mass-Spectrometry; Cancer; DNA repair; Hypoxia; PTMs; Sample fractionation; Database;

    Abstract : Amongst the various –omics sciences, proteomics has the highest potential for functional characterization and consequently can contribute significantly to the field of cancer research. In particular, the focus of this thesis is on breast cancer. READ MORE

  6. 24. Interactions between Streptococcus pyogenes and the human immune system, with special reference to C4b-binding protein

    Author : Anette Thern; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Phagocytosis; M-proteins; M-like proteins; Bovine C4b-binding protein; Streptococcus pyogenes; Human C4b-binding protein; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : The ability of many pathogenic microorganisms to cause infection is dependent on their ability to evade attack by the complement system of the host. One mechanism by which microorganisms may avoid complement attack is to bind complement inhibitory molecules present in the host. READ MORE

  7. 25. SOX11 in Mantle Cell Lymphoma - Novel Tools for Diagnostic, Prognostic and Functional Investigations

    Author : Lena Nordström; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibodies; DNA methylation; Epigenetics; SOX11; Lymphoma;

    Abstract : The goal of biomarker discovery is to identify disease defining molecules, which could be used to improve early detection and/or to predict survival and response to treatment. This thesis is about the transcription factor SOX11, a protein discovered in the context of mantle cell lymphoma in 2008, which shows great potential to be used as a clinical relevant biomarker. READ MORE