Search for dissertations about: "Developmental"

Showing result 16 - 20 of 1228 swedish dissertations containing the word Developmental.

  1. 16. Gene regulation during development by chromatin and the Super Elongation Complex

    Author : Olle Dahlberg; Mattias Mannervik; Peter Gergen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila development; gene regulation; transcription; chromatin; P-TEFb; Super Elongation Complex; KDM4A; H3K36me3; H3K14ac; histone replacement; utvecklingsbiologi; Developmental Biology;

    Abstract : Developmental processes are carefully controlled at the level of transcription to ensure that the fertilized egg develops into an adult organism. The mechanisms that controls transcription of protein-coding genes ultimately ensure that the Pol II machine synthesizes mRNA from the correct set of genes in every cell type. READ MORE

  2. 17. BMP - a key signaling molecule in specification and morphogenesis of sensory structures

    Author : Vijay Kumar Jidigam; Lena Gunhaga; Jonas von Hofsten; Richard A. Lang; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; BMP signaling; Placode morphogenesis; lens; retina; olfactory; otic; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Abstract : Cranial placodes are transient thickenings of the vertebrate embryonic head ectoderm that will give rise to sensory (olfactory, lens, and otic) and non-sensory (hypophyseal) components of the peripheral nervous system (PNS). In most vertebrate embryos, these four sensory placodes undergo invagination. READ MORE

  3. 18. Genetic mechanisms behind cell specification in the Drosophila CNS

    Author : Magnus Baumgardt; Stefan Thor; Angela Giangrande; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; nervous system development; cell specification; stem cells; cell proliferation; combinatorial coding; feedforward loop; Developmental biology; Utvecklingsbiologi;

    Abstract : The human central nervous system (CNS) contains a daunting number of cells and tremendous cellular diversity. A fundamental challenge of developmental neurobiology is to address the questions of how so many different types of neurons and glia can be generated at the precise time and place, making precisely the right connections. READ MORE

  4. 19. Epigenetic Regulation and Reprogramming of the H19 Imprinting Control Region

    Author : Piero Mariano; Rolf Ohlsson; Karl Ekwall; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Imprinting; chromatin; H19; Igf2; CTCF; Insulator; methylation; Boris; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Abstract : The development of a new individual from the fertilized oocyte can ultimately be seen as the consequence of the establishment and maintenance of specific patterns of gene expression. Although regulation of gene activity occurs at different levels, cellular specialization and differentiation are the results of developmental cues that essentially take place at the transcriptional level. READ MORE

  5. 20. Long Noncoding RNA Mediated Regulation of Imprinted Genes

    Author : Faizaan Mohammad; Chandrasekhar Kanduri; Kristian Helin; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Genomic imprinting; noncoding RNA; epigenetics; chromatin; DNA methylation; Developmental biology; Utvecklingsbiologi; Molecular biology; Molekylärbiologi; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : Genomic imprinting is an epigenetic phenomenon that causes a subset of mammalian genes to be expressed from only one allele in a parent-of-origin manner. The defects in the imprinting regulation result in disorders that affect development, growth and metabolism. READ MORE